Of an animal: (a) living under the care of or habituated to humans, domesticated, domestic;—also used of man as a creature [quots. a1398 (1st) & a1400]; also, as noun: domestic animals, domestic fowls; (b) tamed from a wild state, made tolerant of human presence; maken ~, to tame (a wild creature); (c) docile; gentle by nature; also, in conventional comparisons: ~ as a culver; ~ as (like) a lomb; maken ~, to soothe (an animal), calm; (d) of a hound: not diseased, not rabid; of a serpent: harmless.

(a) Of a plant, tree, fruit, etc.: cultivated; also, as noun: a cultivated variety of a plant; (b) of a land or place: civilized, settled; also, as noun: settled land.

(a) In a state of subjection, physically subdued, overcome, defeated; also, bested in a contest [1st quot.]; maken ~, to subdue (sb.), overcome (sb., a nation) in battle; reduce (sb.) to a state of subjection; (b) maken ~, fig. to subdue (the flesh), restrain (lechery), bring under control (men governed by the flesh); (c) maken ~, to render (sb.) harmless; (d) economically subordinate; maken ~; (e) fig. brought low in fortune.

(a) Of a person, the heart: meek, gentle-natured; tractable; compliant; also, intent on homely activities, domestically inclined; civilized; (b) as noun: one who is mild-natured or gentle; (c) well disposed (toward sb.), favorably inclined; (d) med. of a medicinal preparation: gentle-acting, mild in its effects.

In generalizing phrases, often as rime tag with diminished force: (a) ~ and wilde, of all sorts; (b) as noun: bothe fremed and ~, bothe) wilde and ~, everyone, all people; every creature; everything; neither wilde ner ~, nothing; of wilde and of ~, of everyone; bothe of ~ and wilde, of wilde and ~, of everything.

Anat. & med. Of a fistula: inner, interior; also, as noun: a bone in inner position.