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Opium works upon the Spirits, as Drugs do upon the Liver, in the Body; it is good in Feavers, for in all Feavers the Spirits are like Wanton Bodies, which run and play so much, untill they have put themselves into a Fiery Heat: But dull Opi∣um corrects them, like a grave Tutor; wherefore Opium should be good for Mad-men, moderately taken.