(a) Of persons, the soul, etc.: obstinate in wrongdoing, willful, wicked, perverse; also, of a path, way: crooked;—used in fig. context; (b) as noun pl.: those who are obstinate or perverse, the……

To be in opposition, be at variance, conflict. …

Of persons: obstinate in wrongdoing, perverse; of conduct, deeds: evil, iniquitous; of a thought, deed, etc.: sinful, wicked, depraved; also in fig. context. …

Perversely, iniquitously. …

(a) An instance of perversity; (b) pl. trials, burdens, afflictions. …