(a) To destroy or annihilate (something); to annihilate (the earth), wreck (a building), ruin (the fertility of soil); to obliterate (a painting, a stain), cover up (a well); (b) to devastate, pillage, or ravage (a country, city, etc.); also, to ruin (a country by misrule); (c) to be destroyed, perish.

(a) To put (someone) to death, to kill; (b) to ruin (someone), bring into disgrace; to lead (someone) to ruin or perdition; (c) to condemn or damn (someone); fordon and fordemed, condemned and doomed.

(a) To render (something) ineffective or useless; to frustrate; (b) to prevent (something), keep (an event) from taking place, prevent (someone from doing something); (c) to defeat (an enemy), to overcome (an obstacle, a danger).

(a) To vitiate or invalidate (something), abrogate or annul (a law, a right), abolish (a custom), discard (a doctrine, a commandment); (b) to break or violate (a law, pledge, commandment), infringe upon (a king's authority); (c) to forfeit (a right).

(a) To ruin or destroy (a virtue, affection, hope, fame, health, etc.); (b) relieve or dispel (grief, pain, disease, etc.).

(a) To drive out or overcome (sin, temptation, etc.); also, to obtain forgiveness for (sin); (b) to blot out (sin); to do away with (another's sin) by atonement.