syphilis, however, that Warthin is best known. Interested first in the lesions of congenital syphilis, he early recognized that the histopathological manifestations of syphilis exhibit an essential unity in various organs and at various stages of the disease. In a series of some forty papers he established a new conception of the pathology of late, and of latent, syphilis, particularly in the heart, aorta, pancreas, adrenals, and testes. Making use of new techniques in staining, developed in association with Allen C. Starry, Richard E. Olsen, and Robert Farrier, he was able to support his views of this disease process by the demonstration of Treponema pallidum in lesions in which it had never before been seen.
For many years medical students used Dr. Warthin's translations and revisions of the tenth and eleventh editions of Ziegler's General Pathology as well as his own Practical Pathology and Autopsy Protocols. In the later years of his life his writings reflected to a greater extent his interest in the cultural and philosophical aspects of medicine. During this period he brought out three books: Old Age (1929), The Creed of a Biologist (1930), and The Physician of the Dance of Death (1931).
Warthin held office in many of the societies in the fields of medical biology, pathology, and internal medicine of which he was a member. He was president of the American Association of Pathologists and Bacteriologists in 1908, of the International Association of Medical Museums from 1910 to 1913, of the American Society for Experimental Pathology in 1924, of the American Association for Cancer Research and of the Association of American Physicians in 1928, and of the American Association of the History of Medicine in 1930-31.
Warthin, in collaboration with Dr. M. E. Abbott and others, edited the Bulletin of the International Association of Medical Museums (1911-31), the Annals of Clinical Medicine (1924-27), and the Annals of Internal Medicine (1927-31).
Untiring energy, broad cultural attainments, personal fastidiousness, and unswerving loyalty to his chosen interests were Warthin's prominent traits. He was a vigorous and outspoken proponent of that which he believed to be right. Thus, he made many enemies as well as many friends. Students considered him a hard taskmaster, and those who had little personal contact with him generally disliked him. To the individual student, however, he was always ready to give sympathetic encouragement, and his friendly and understanding attitude toward the individual was in sharp contrast to the pedagogical pressure which he put upon his students en masse. He was fully aware of the feeling of the average student toward him and frequently reacted with the statement that he was quite willing that the students should swear at him while here, if they would swear by him after they were out in the practice of medicine. This hope was amply realized, and many who had been outspoken in adverse criticism as students, returned to voice their appreciation and to assert that from pathology, more than from any other one department, they had gained the knowledge which enabled them to succeed in practice.
Between 1903 and 1931 all junior work in general pathology was transferred to the preclinical years, the required autopsy work was greatly increased, specialized undergraduate courses were introduced, an expanded summer program was established, and an ambitious program of research and of extramural service was carried out.
Activities in connection with world war I. — The teaching load of the Department of Pathology was practically