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1652 INFLUENZA-FRIE
APPARATUS FOR ADMINISTERING ARSPHENAMIN AT
TEMPERATURE OF BLOOD*
S. R. THOMPSoN, M.D., CHARLOTTE, N. C.
This apparatus was suggested on account of severe reaction
and sometimes death after the administration of arsphenamin
intravenously. Physicians are realizing more and more the
necessity of introducing solutions that will be free from all
possible sources of irritation. The reaction called "chills and
fever" following intravenous injections of arsphenamin is
due, we believe, to injecting arsphenamin intravenously below
the normal temperature of the blood.
In giving ten or more doses of arsphenamin within from one
to four hours we discovered that the patients receiving treatment when the solution was hot, or at the temperature of the
blood, had no reaction or chill. Those receiving the last
doses of the solution, which had cooled below the normal temperature of the blood, nearly always had more or less reaction. We have given more than a thousand doses by this
method in dosages of from 0.3 to 0.6 gm. Solutions of from
30 to 150 c.c. have been given with chills or severe reaction
in less than 5 per cent. of the cases.,
The apparatus consists of a glass container practically closed
with a wooden cover -
to prevent the entranceof cold air. In the
center is a regular
arsphenamin graduate.
In the air chamber "
around this there are
three 10'watt incandescent lights and a
thermometer, registering in Centigrade and
Fahrenheit. The lights
may be attached or on
separate switches. The_
rubber tubing, mixing
jar, needles, etc., may
be of any type desired.:
These are not included
in the illustration. Before the injection is
begun the solution in
the rubber tube can be
brought to the proper Apparatus for administering arsphentemperature by being amin at the temperature of the blood.
allowed to. run back
into the graduate. Solution left in the apparatus will remain
at the desired temperature, depending on the number of lights
used.
The simplicity, practicability and economy of this apparatus
have commended it to us, and it has become indispensable in
our.clinic.
* Presented before the Mecklenburg County Medical Society, May"
5; 1918.
* From the Crowell Urological Clinic and United States Public
Health Clinic.
Venereal Diseases in Army and Civil Life.-In these five
camps (Dix, Lee, Upton, Meade and Pike) there were about
nineteen times as many cases contracted before enlistment
as afterward. It is, therefore, the disease contracted by
civilians before enlistment, under civil conditions, which is
responsible for the disability due to venereal disease in the
Army. To reduce the small amount of venereal disease contracted after enlistment is the problem of the Army. To cut
down -the vast amount brought in from civilian life is the
problem before the state and local health officers throughout
the United States. There is no greater or more urgent health
problem before them today. To solve the whole problem, the
Army and the health officers will need to exercise the closest
cooperation.-Major W. A. Sawyer, M. C., U. S. Army,
Am. Jour. Pub. Health; September, 1918.
'L
DIANDER ET AL. Joua. A: M. A.
Nov. 16, 1918
Military Medicine and Surgery
THE EPIDEMIC OF INFLUENZA AT
CAMP - SHERMAN, OHIO
ALFRED FRIEDLANDER, M.D. (CINcINNATI)
Major, M. C. U. S. Army; Chief of Medical Service
CAREY P. McCORD, M.D. (DETROIT)
Major, M. C., U. S.- Army; Chief of Laboratory Service
FRANK J. SLADEN, M.D.. (DETROIT)
Captain, M. C., U. S. Army; Assistant Chief of Medical Service
AND
GEORGE W. WHEELER, M.D. (NEW YORK)
Lieutenant, M. C., U. S. Army; Bacteriologist, Laboratory Service
CAMP SHERMAN, CHILLICOTHE, OHIO
At the time the prevailing epidemic of influenza
was at its height in New England, numerous cases
of coryza and bronchitis appeared at Camp Sherman.
The picture was not characteristic of influenza, but the
condition was so frequently noticed among the patients
of the base hospital that isolation was instituted and
special wards'set aside for this purpose. The absence
of the usual features of influenza led to considerable
TABLE 1.-PNEUMONIA AT CAMP SHERMAN *
Date Admissions Pneumonia Deaths
Sept. 24.................. 80 0 0
Sept. 26..................... 216 8
Sept. 27......................321 10 1
Sept. 28......................314 9J 3
Sept. 29...................... 303 27 2
Sept. 30...................... 732 97 7
Oct. 1................ 1,157 26* 15
Oct. 2...................... 644 278 22
Oct. 3......................633 55* 45
Oct. 4.............957 - 461 52
Oct. 5.............. 711 214 104
Oct. 6....................449 152 119
Oct. 7..-.'...'..'.....- 444 160 110
Oct. 8.....................169 73* 125
Oct. 10...................... 227 160 86
Oct.' 11............. 78 - 51 53
-Total....... 7,618 2,001 842
* Marked irregularity exists in these figures, but the variations in the
daily occurrenee of' pneumonia are apparent and not real, being due
to the system of reporting diagnoses.
comment as to the justification of such a diagnosis.
This uncertainty was abruptly and definitely terminated
by the sudden appearance of large numbers of patients
exhibiting characteristics of clinical influenza. Unlike
the simple -syndrome of the earlier cases, the new group
was featured by sharper onset; prostration, aches
and p'ains, and high temperature. By September 24
the transition had occurred, and this date marks the
beginning of a definite epidemic of clinical influenza.
At this time the population of the camp was 33,044
Of this number, 24,513 were white, and 8,52 were
colored. The larger numbers of these me ere
inducted into military service from Ohio, but tller
groups from Pennsylvania, West Virginia, Ak ina,
Tennessee and Louisiana. Of the total population,
-15,493, or 46.8 per cent., had been in service one month
or less.. From the nature of the examinations and
procedures incidental to induction into service,-it followed that these men were more closely and frequently
grouped than the other men of the command., An
analysis of the first 4,269 cases of influenza reveals
that 2,944, or 69 per cent., occurred in men who had.
been in service one month or less. In other worde
two thirds of these cases occurred in a group, of 15,493