Doron medicum, or, A supplement to the new London dispensatory in III books : containing a supplement I. to the materia medica, II. to the internal compound medicaments, III. to the external compound medicaments : compleated with the art of compounding medicines ... / by William Salmon ...

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Title
Doron medicum, or, A supplement to the new London dispensatory in III books : containing a supplement I. to the materia medica, II. to the internal compound medicaments, III. to the external compound medicaments : compleated with the art of compounding medicines ... / by William Salmon ...
Author
Salmon, William, 1644-1713.
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London :: Printed for T. Dawks, T. Bassett, J. Wright and R. Chiswell,
1683.
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Subject terms
Pharmacopoeias -- England -- Early works to 1800.
Dispensatories.
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"Doron medicum, or, A supplement to the new London dispensatory in III books : containing a supplement I. to the materia medica, II. to the internal compound medicaments, III. to the external compound medicaments : compleated with the art of compounding medicines ... / by William Salmon ..." In the digital collection Early English Books Online 2. https://name.umdl.umich.edu/A60600.0001.001. University of Michigan Library Digital Collections. Accessed June 8, 2024.

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CHAP. XXII. Examples in compoundin Opiates, and Cor∣dials or Antidotes.

1. BEfore we come to the Exemplary part of compounding O∣piates, (that this our Opio∣logia may be compleat) we shall shew you the Kinds, Natures, Qualities, and se∣veal Operations of Opium, both good and evil: and because that Famous and Learned Man, Dr. Willis, has exquisitely performed the same, we shall (ceasing at present our own Concep∣tions) give you here the E∣pitomy of what he has said

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concerning Opium in parti∣cular, and Opiatick Medica∣ments in general; but in a different Method.

2. The Kinds of Narco∣ticks are several, as Purslane, Lettice, Hounds Tongue, Nightshade, Henbane, To∣bacco, Mandrakes, Poppies, red, white, and black: be∣sides some other Simples ex∣treamly venomous, and so never medicinally prescribed. The Juyce and Seeds of Henbane are much used in some Hypnotick Compositi∣ons: Mandrakes are seldom used. Hounds Tongue having a plain soporiferons Odour, shews it's narcotick Nature; it is a very neat Plant, with soft Leaves; and in it's flou∣rishing Time, is crowned with a bright Red, and most delicate purplish Flowers: the Powder of it's Roots goes into that famed Opiate called Pilulae de Cynoglosso: the juyce of the whole Plant gathered about the begin∣ning of the Spring, being expressed and depurated by a close and warm Digestion, and decanted from it's Fae∣ces, yields a clear Liquor, and splendidly redish, and blushing like a Ruby. This may be used either for a Menstruum, for making up of Narcotick Confects: Or, for to make an Hypnotick Syrup: Or lastly, It's Humi∣dity being evaporated, to make Tinctures and Ex∣tracts out of it, as is done out of Opium. Lettice and Purslane are used to make Syrups of, which is done of their expressed Juyce; which Syrups, are commonly given to Children, and very aged People, (where Opiates may prove dangerous) because they very gently, without any Prejudice, enduce Rest and Sleep, and sometimes Indolency, as in Fluxes, Gripings of the Guts, and such like. Nightshade is used to cause Rest by outward Application, to the Temples; chiefly, it's depurated Juyce, or distilled Water is taken, and being mixed with Rose∣water, the Temples are bath∣ed therewith, then a Rose-Cake very hot, and dip'd in the same, is forthwith to be applyed to the said Parts, and so bound on. Tobacco

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is accounted as a Narcotick, although never put into Narcotick Compositions; because its Fume taken in a Pipe, produces the same Ef∣fects as they; yea, it doth the same thing with our Country-men, as Opium does with the Turks, to wit, ei∣ther of them by affecting the animal Spirits, by an un∣accustomed manner, and by rendring them as it were astonished, disposes them to the doing or suffering of any thing without any great sence or trouble of Weari∣ness; it renders them fear∣less of dangers, and makes them patient in Hunger, Cold, and Labor. When any one first begins to take Tobacco, he is for the most part affected with a Verti∣go, and Scotomia, then a cruel vomiting, and some∣times purging follows, the Feet grow weak, the man staggers, the Hands tremble, the Tongue faulters, or speaks at random, and some∣times a cold Sweat, and terrible Swooning follows. The cause of all this, is, from the Animal Spirits being, as it were, intoxicated by the Narcotick Sulphur, which are distracted very much in their whole Dominion, and are agitated into Ataxias, or Ir∣regularities. But this Fume once becoming familiar and customary, it is on the con∣trary grateful, and takes the Animal Spirits with so great a Witch-craft, or pleasing Allurement, that some had rather be forbidden Meat or Drink, than the use thereof. The reason of which is, that this Fume being once made familiar with the said Ani∣mal Spirits, gently awakes, or stirrs them up at any time being sluggish and sloathful, and as it were tickling of them, provokes them into gentle and expansive moti∣tions, with which they are wonderfully recreated, as with the drinking of Wine.

3. The red Erratick, or Corn Poppy, has a great Hyp∣notick Quality, much great∣er than any of the for∣mer things, though far less, more gentle, and more be∣nign, than that of the white or Black Poppy; and there∣fore

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in some cases it is very needful, and may be more secure in its use. From this Poppy, the Apothecaries pre∣pare a distilled Water, and a Syrup, which are many times with great advantage given in most continual Fe∣vers, and are thought to be absolute Specificks in the Plcurisy, because they truly take away pains; and by stopping somewhat the pulse, depress the feverish Aestuation of the Blood. Em∣pericks prepare a Tincture from the Flowers with S.V. which has the aforesaid Vir∣tues, & have been oftentimes proved effectual against Sur∣feits: the reason of which seems to be, that the Spi∣rits of the Wine preserve the Contents of the Sto∣mach from putrefaction; and the Narcotick Sulphur of the Flowers, resist the violence and heat of the as∣saulting Fever.

4. The White Garden Pop∣py is the next to be consi∣dered: From the Heads and Seeds of this Poppy is made Diacodium, both liquid, as in Syrrup; and solid, as in Tablets or Lozenges, and that according to the pre∣scripts of many famous men; from the same Decoctions, expressed Oyls, Emulsions, and other Hypnotick Confects are made: This Poppy abounds much more with Narcotick Sulphur than the former, but with much less than the Black, of which Opium is made; and therefore the Medicines aforenamed pre∣pared from the White Poppy, as they contain less of the said Sulphur, so are they much more pure and Inno∣cent, and are oftner and more securely given than a∣ny thing made of Opium: For it is not convenient to use Laudanum or Opiates, unless, when for the vehe∣mency of Symptoms in any Disease, Diacodiates will do little or no good. And as Diacodiates (which are preparations from the White Poppy) contain in themselves less of the said Narcotick Sulphur, so they want not much preparation; but be∣ing simply made by Infusi∣on, Decoction, or Expressi∣on, they may be brought in∣to

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a medical use; whereas Opiates (which are prepa∣rations from the Black Pop∣py) containing in themselves a vast quantity of the said Narcotick Sulphur, are com∣posed, corrected and made by divers and various prepa∣rations of a much higher Nature, that thereby they may become safe and pra∣cticable.

5. The Black Garden Pop∣py, is that of which our Opium is made, being a con∣creted Juice flowing from the wounded Heads or Leaves of the said Poppy be∣ing ripe: and from this Black Poppy, nothing more is taken for a medical use than the said Opium, which is a Tear or Gum flowing as a∣foresaid. There are several kinds of this Opium; but the best is the Thebian, being hea∣vy, thick, strong-scented like Poppy, bitter and sharp, in∣flamable, almost of the co∣lor of Aloes, and easily dis∣solvable in Water, or almost any other Liquor. See our Pharmacopaeia lib. 1. cap. 8. Sect. 50. where you may see the various preparations thereof: its preparation with Adjuncts, or rather Compositions are divers and many. The most famous Opiates of the Ancients are Pilulae de Cynoglosso, Requi•••• of Nicholaus, and Philonium, which last is fourfold, viz. Roman, Persian, Magistrale of Mesue, and Tarsence of Gale. The Opiates of Neotericks from the Praise-worthiness of the same are commonly called Laudana, and by some Nepenthes, from their taking away pain: these ought not to be admitted into practice, unless invented by skilful Men, and of which long tryal has been made, of which there are many pub∣lickly extant, received and approved of, the chief of which, are those of Para∣celsus, Crollius, Quercetan, Hartman, Mynsicht, and Hel∣mont. The first five of which are composed only in the form of an extract, whose Basis or Ground is the Tin∣cture of Opium drawn forth with a fit Menstruum, and then corrected with Saffron, Castor, Bezoar, Pearls, spe∣cies Diambrae, and several

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precious Chymical Oyls. That of Helmont is a liquid Tincture of Opium, drawn with Juyce of Quinces fer∣mented. And this may be given ab ℈ss. ad ℈j. or somewhat more in any Cor∣dial Vehicle, where the use of a Pill cannot be admit∣ted.

6. In treating about these 2 sorts of Laudana, we ought to have great respect to the Menstruum. Some use S. V. because they think Opium cold: others Spirit of Vine∣gar, or Juyces of Citrons or Limons, because they think the Opium hot (as in∣deed it is) but this signifies nothing in respect to the heat or cold of the Opium, but in respect to its Narco∣tick Sulphur, thereby to cor∣rect it. The Ancients cor∣rected it with things hot in the fourth degree, as Py∣rethrum, Euphorbium, Pepper, &c. out of a supposition that it was cold in the fourth (but is indeed hot:) how∣ever those Correctives be∣came most proper, because these biting sharp things, be∣ing full of a volatile Salt, do predominate over the Narcotick Sulphur of the O∣pium, and break its potency. Helmont used the Juyce of Quinces put into Fermenta∣tion; but Dr. Willis com∣mends the S. V. impregna∣ted with the volatilized Salt of Tartar: Or the Tincture of the Salt of Tartar brought to the highest Red by long digestion, which is the Ba∣sis of his Liquid Laudanum, adding for its Complement, Saffron, Castor, Cloves and Lignum Aloes: the Dose of which is, ab gut. xv. ad xx.

7. Opium consists of a vast quantity of sulphurous par∣ticles, mixed with some sa∣line volatile particles, with a little quantity of Earth. That sulphurous particles do abound in it, is manifest to Sence, to wit, from its strong Odor, and its Inflammabi∣lity. The Volatile Saline par∣ticles are evident in its sharp∣ness, bitterness and prick∣ing; as also from the Vola∣tile Property of the Opium, and its speedy ascending to the Head, and intangling of it self with the saline vo∣latile

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Spirits of the Brain; the Earth is apparent. Hence it appears, that since a Narcotick Quality is con∣tained in the Opium, that it is chiefly lodged in the Sulphur thereof, because it is oftentimes found so hurt∣ful to the texture of the A∣nimal Spirits, which its sa∣line property would rather cherish, as sympathizing with them. Now because the Animal Spirits may be of a differing texture in di∣vers Bodies, therefore Opi∣ates may work more strong∣ly and virulently on some than on others. The Turks, who have an adust Blood, and in whom more fixt Spi∣rits and less volatile are bred, cat Opium without hurt, or at least without danger of Life; but the Europeans, who have more subtil and purer Spirits, can∣not do so. Dogs will de∣vour Opium in a great quan∣tity, without either Sleepi∣ness or Death; but a small Dose of it will presently kill a Cat: for that the Spi∣rits of this Creature are so very volatile and pure, that that they cannot at all en∣dure the Narcotick Sul∣phur.

8. Opiates as they are en∣dowed with many great Vertues and excellent Pro∣perties, so also have they some evil ones, and often∣times deadly effects. We have seen it by the sad ex∣perience of some, who have no sooner taken an Opiate, but they have fallen into a perpetual Sleep; and some, who by taking too great, or untimely a Dose, have ren∣dered their Lives unhappy and unprofitable afterwards, by the hurt of the princi∣pal Faculties: Some by ta∣king one Dose, have fallen into so profound a Sleep, that they could never be awa∣kened. They have lived in∣deed 3 or 4 days, having their Pulse, Respiration and Heat well enough; yet not to be recalled to Sence and Waking, by any Medicines or Tortures: Some by ta∣king it, have slept mode∣rately, or almost nothing at all; yet not long after, have grown very bad, languish∣ed, drawn their breath very

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difficulty, their Pulse, natu∣ral Heat, and Strength of Body momentarily decay∣ing, in such sort, as not to be restored by any Cordials; these lingring on by degrees lost their Lives. One by taking an Opiate, has pre∣sently fallen into his last and deadly Sleep, complain∣ing of a great weight and coldness of his Stomach, by and by he was affected with a notable Languor, a sink∣ing down of his Spirits, and a coldness of the extream parts; and within a few hours after, complaining of the dimness of his Sight, and then of quite Blindness, he streightway expired. The reason of this suddain destroying of Life is this, that the Narcotick Particles of the Opiate, do forthwith, and vehemently affect either the Cerebrum or Brain, or the Cerebellum, where, by oppressing the Animal Spi∣rits, as well the outmost Spirits as the internal or inmost, they become great∣ly profligated and over∣thrown; where by their Forces, being altogether suppressed, then presently a deep Sleep, or an invincible Drowsiness and Stupefaction follows, which forthwith induces Death, the Pulse and Respiration being in a good state for some time.

9. As for the harms that Opiates may do, they are not by me to be all here e∣numerated. In the Head, they sometimes hurt the chief functions of the Mind, as Memory, acuteness of Wit, Discourse: Sometimes the frequent use of Opiates causes loss of Memory, and sometimes a Lethargy; and sometimes it does these e∣vils, by being given in too large a Dose. In some it has caused a Stupidity of Wit, and in others perfect madness. The reason of these things, is as before declared, for that the Nar∣cotick Sulphur first and chief∣ly assaults the Brain, where, whilst it destroys or profli∣gates some Animal Spirits, it perverts many others from their wonted ways of Ema∣nation, and leads them in∣to devious or unusual Paths. In the Breast and Praecordia,

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it clearly appears, that they do sometimes hurt the Vital Actions, from their depressi∣on of the Pulse and Respi∣ration, causing them to grow languid, or weak and difficult, and by degrees, wholly to cease: wherefore in Fevers, where the Blood being greatly depraved, yields but very few and weak Animal Spirits, Opiates are for the most part hurtful, and as it were poy∣sonous: For though in the Plague, and other malignant Fevers, Mithridate, Treacle, Diascordium, yea and Lau∣danum are often given with good Success, yet it is while the Pulse and Respiration are strong; but if in those Diseases, or other Fevers they be weak, these famous Antidotes are but very spa∣ringly to be used; but stronger Opiates not at all: Also in a vehement Cough, or Astmah, Empyema, and in other diseases of the Breast, where Nature is suddainly provoked to the casting out of what is troublesome to the part, and urges it with great endeavor, we must abstain from Opiates no less than from Poyson; because they increase the matter to be removed and fix it; and also weaken the parts which ought to expell it. In the Belly and Bowels, Opi∣ates being often taken, are sometimes injurious to the principal Faculty, viz. the Appetite, or desire to eat, on which depends all Nourish∣ment, and the root of Life. And the reason is, because the concoctive Faculty of the Ventricle is debilitated, and the excretory motions of the Intestines made slug∣gish, from the Stupefaction or Hurt of the Spirits in∣habiting the Interior Coat of the Stomach and Guts, so that those nervous Fibres, although empty, are no more corrugated, from which cause all hunger cea∣ses. And it is a common Observation, That want of Appetite, and Slothfulness of the Belly, are the familiar effects of Opiates.

10. How Opiates do af∣fect the Animal Spirits, has been already in part decla∣red; not by raising Vapors

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into the Head, as some have thought, nor by opening the Pores of the Brain, there∣by to admit the soporiferous matter; but only by de∣stroying or profligating some Animal Spirits, where∣fore the rest, as being ama∣zed, or compelled more in∣wardly, or at least being called back from their won∣ted efflux into the Nervous Parts, do relinquish, or remit for a while their required Tasks. This is evident, be∣cause Opiates taken in too great a Dose, do destroy the Animal Spirits so abun∣dantly, that they cause Death; whereas given in a just dose, and to a fit object, although they may cause an Overthrow and Amazement of some Spirits, yet they only allay the too great fierceness and impetuosity of the sensitive Soul, that she, sinking down, as it were, within her self, may lie qui∣etly, or at rest and ease. This Property of Opiates consists not in apparent qualities, as of Heat or Cold, nor in any occult Quality; but in Par∣ticles, much contrary to the Animal Spirits, and which may be said to be Extin∣guishers of them; but in what kind of Subsistencies the contrary particles of ei∣ther kind are, will be hard to shew, because not ob∣servable by the Sence. The Animal Spirits are thought to be most subtil Particles, composed of Spirits and vo∣latile Salt, united together & highly exalted: So Opiates, on the contrary, may be thought to be composed of stinking Sulphur, with Salt, and an Earthy Matter, so much opposite to the subtil Texture of the Animal Spi∣rits, that sometimes they profligate them at a di∣stance by their meer Effluvia.

11. Now the places in which Opiates do first and chiefly begin to operate, are thought to be at the Shell of the Brain, to which, up∣on the Opiatick Particles ap∣proach, the Spirits dwelling there, (they being, as it were, the Watchmen that first of all) recede, and indulge the Body to Rest and Sleep; and it is just so to think: For the Particles of every

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kind of Opiate, after it is taken, being carried into the Blood, and circulated with it, doth chiefly exercise its Narcotick Quality, near the Shell of the Brain: for they meet within this place the first Opposition, and forces the Animal Spirits, and de∣stroy, or rather extinguish wholly, many of these Spi∣rits placed in the fore part of the Battel; the other Spirits of this place not de∣stroyed, go back, and by their Emanation being re∣strained, fly towards the middle of the Brain, thereby indulging Rest and Sleep; but yet by what means in so short a space, viz. some∣times before it can be dissol∣ved in the Ventricle, it should cause such an Operation, is not easie to unfold. To this however we say, that the Journey from the Ven∣tricle, by the Blood, to the Head, is very expeditious, and may be performed in a very little time: But should not this be granted, it is probable that Opiates may act more immediately on the Ventricle, and by its mere Contact (from a con∣sent of the stomatick Nerves, with those of the Par Va∣gum in the Brain) procure the said Rest and Sleep, be∣fore there can be any Com∣merce of the Particles of the Opium with the Blood; and hence it is, that if the Stomach is afflicted, the Head is not well, the affli∣ctions and evils of either of them, do afflict each other. Thus it appears, that the places where Opiates first exert their Power, are the Ventricle and Cortex of the Brain, and from acting on those parts, they first begin to procure sleep.

12. How far, or into what part Opiates do ex∣tend their Vertues, we shall now speak, and shew the Sphere of their Activity. By what has been already said, it appears plainly, that they act upon the Animal Spirits: but whether the Blood, and other Humors are hurt thereby, remains to be questioned. Certainly the Blood is not at all vitiated by them: This we judge, First, from their so very

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little Dose, by which it is not probable that the whole Mass of Blood should be corrupted thereby. Second∣ly, for that though Narco∣ticks be often applied, no Pustles, or little Whelks ap∣pear in the Skin or Viscera, as is wont to happen when the Blood is empoysoned, or but a little corrupted, as it were, by an ordinary Surfeit. Also those with whom Opiates are become familiar, are not hurt in their Animal Spirits, altho' daily taken in a great quan∣tity, so that no Dyserasy of the Blood can come from thence. However it is not to be thought that the Par∣ticles of Opiates, either a∣gree with, or are assimila∣ted to the Blood, but are rather wholly Heterogenous and immiscible: for they no sooner come into the Mass of Blood, but they are suddenly expelled from it, and from thence being partly cast on the Cortex of the Brain, cause Sleep; and partly thrust forth by the Pores of the Skin, stir up Sweat, and for the most part an itching. As to the other Humors, we see not how Opiates do any ways hurt the Serum, or Nervous Juyce, or the Chylous Juyce, so that their Vertue and Power seems chiefly to ad∣here to the Animal Spirits. From hence we judge, that Opiates given in a just Dose, only reach the Spirits in the Cortex, and stir up no more than a natural Sleep; the Pulse, Respiration, Con∣coction, and Separation of Humurs being performed af∣ter their wonted Custom. But if it be given in too great a Dose, it imposes more strong Chains on the Spirits of the Brain and its Appendix; and if the Dose be yet greater; it inlarges its Narcotick Force, even to the Cerebellum, whereby the Appetite is destroyed, Re∣spiration very much streight∣ned, the Pulse fails, as also the motion of the Heart; so that there happens as it were an Eclipse of all the Facul∣ties, a cold Sweat and a per∣petual Sleep, whereby the motion of the Heart quite ceasing, the vital flame is ex∣tinguished.

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13. It remains now that we enquire into the good effects of Opiates, and how they may be given to the Safety and Benefit of Hu∣mane Life. As to their good Effects, they are ei∣ther on the Animal Spirits, or on the Blood, or in the Humors; the former are indeed first or more imme∣diately affected; the other only secondarily, and by means of the affected Spi∣rits. And indeed Opiates seasonably, and in just dose administred, in the too great and irregular motions of the Animal Spirits, may bring notable Relief; as al∣so in faults of the Internal Sences, which are Watchings and Delirium; and in Vi∣ces of the External, the chief of which is pain. Now the Irregularitis which Nar∣coticks rectifie, are violent and too swift Pulse, Con∣vulsions of the Praecordia or Viscera, and the too violent and excessive Excretions of these; so there are many and divers cases, in which, whilst the Animal Spirits like fierce and furious Hor∣ses, run about, or leap be∣yond their Bounds; they ought to be reduced or re∣strained by Opiates, as it were with Bridles.

14. That they help a∣gainst unnatural Watchings, Experience has confirmed; and the reason is known Philosophically from the cause of want of Sleep: which is chiefly from the Animal Spirits, being car∣ried too much forth, and being of themselves unqui∣et, whereby they blow up, and irradiate both the sen∣sory Organs, and possess e∣specially the outmost Border of the Brain, or the Cortex so called; where the Opia∣tick Particles being carried, either by the passage of the Blood, or otherwise, do forthwith destroy or profli∣gate those watchful Spirits, and make those which are next to them, to fly more inwardly, whence Sense and Motion being in some measure hurt, and the Spi∣rits kept from their Ema∣nation, a Dulness and Drow∣siness presently seizes, and immediately after that, a

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sweet and pleasant Sleep.

15. In a Delirium, an Opiate is for the most part given with good Success (tho' sometimes they may hurt also:) For when the Spirits are too much stir∣red up within the Brain (by the force of any other cause) and struck as it were with a Fury, they fly beyond their wonted Bounds and Passages; then the Opi∣ate approaching towards the Cortex of the Brain, re∣presses them, and stops them a little while from their Motion, and this as often∣times as it is repeated, till at length the Spirits return into their ancient Channels, and rightly perform their Duties.

16. For easing all man∣ner of Pains whatsoever, Opiates may deservedly be called Nepenthe, and are tru∣ly a kind of Divine Reme∣dy; insomuch as we can scarcely enough admire how an almost intollerable pain, whether in any Member, or in the Viscera, is, as it were by Inchantment, of a sud∣dain taken away, or made at present to cease, by the taking of a very small Dose of these Remedies, yea some∣times without Sleep, or at least before Sleep comes: And it is yet more stupen∣dious, that whilst the Opi∣atick Particles do continue to operate, and sometimes a little after Sleep is ended, that there is a high Allevia∣tion, and Freedom from Pain in the part afflicted, which ease continues, till the Force of the Medicine is spent, after which the pain returns again as before: now in the Opiates casing of pain, the Question is, by what means or artifice it does it, whether its Narco∣tick Power is employed on the afflicted part, or on the common Sensory, or on the whole sensible Soul?

17. The reason of the Difference of the former Proposition is, because pain being excited in one place, is felt in another, and its effect is poured forth through the whole sensitive Soul: Now the Production of Pain consists in this, that the Nervous Fibres are

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irritated very much, and pulled one from another, by some incongruous and great∣ly unproportionate thing, so that the Spirits abound∣ing in them, are by and by distracted; and put into confusion, by being snatch∣ed from their equal expan∣sion. But the Sense of the pain is caused by a certain Undulation of the Spirits, through the Nervous Pas∣sages of the Common Sen∣sory; which sort of affecti∣on still proceeding even to the middle of the Brain, stirrs up the Imagination, from whence being present∣ly reflected through the whole Hypostasis of the Spi∣rits, diffuses that certain Disaffection and Inquie∣tude.

18. Hence it is, that as oft as Opiates induce Sleep, an Analesia, or Cessation of pain presently follows. For the Spirits which actuate the first Sensory, are by the Opiatick Particles also bound with the Spirits inhabiting the Brain; for which cause, although the paining part be irritated, yet the sense of all pain is inhibited. But now when the Sick awakes, that he should continue free from pain for many hours, become lively, and exercise exquisitely all the Animal Functions, till the strength of the Medicine is spent; and then the Pain present∣ly to return again, accor∣ding to its old Exorbitancy, is a thing worthy to be en∣quired into.

19. For the solving of this Question, we think not that the Spirits of the grieved part, nor those of the com∣mon Sensory, either singly; or both, are bound by the force of the Opiate, it can∣not be believed its Particles could penetrate so deeply as to enter into the Brain and Nervous Stock, and in so short a time descend to the part afflicted, suppose a Finger or Toe. Since there∣fore the Analesia, or Cessa∣tion of Pain after Sleep for some Hours can be refer∣red neither to the grieving part, nor to the First Sen∣sory, stupified by the Opiate; let us see how the reason of this may be deduced from

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a certain Narcotick Affection of the whole Sensitive Soul.

20. First, it is necessary absolutely for the stirring up, or continuing of any Pain, that there be a great plenty of Spirits abounding in the part afflicted. For their mutual Allision, or beating one against another (causing a Distraction and Excandescency) is the con∣junct Cause of all Pain: Wherefore, if there be a calling back of the Afflux of Spirits into the Brain, to supply the place of those which are destroyed or pro∣stigated by the Powers of the Opiate, or to help to maintain the Contest with the Opiatick Particles; it follows, that the Pain must necessarily cease, and so long, till the part pained is supplied again with such an Afflux of tumultuating Spi∣rits, which cannot be done by the Spirits in the adja∣cent Fibres: For they lie so thinly dispersed every where, that they scarcely touch one another.

21. Now this withdraw∣ing of Spirits here necessary for the causing an Analesia, or Cessation from Pain, can be produced by no o∣ther Remedys whatsoever, but only by Opiates: For truly not only the outmost, and as it were percursory Spirits, are destroyed by the Opiatick Particles en∣compassing the Borders of the 〈 in non-Latin alphabet 〉〈 in non-Latin alphabet 〉, but the first springing forth of these Spi∣rits, within the Brain or Cerebellum, and for that cause, their Efflux upon the Nervous Stock, are forth∣with greatly suppressed; so that during the Power and Force of the Opiate, they are much more sparingly dispensed; and yet less in∣to the Praecordia, Viscera, and all other Extream Parts.

22. Hence it is, that the Pulse and Breathing, do re∣mit of their Vehemency and Quickness, even because of the suppression of the Afflux of Spirits from their genera∣tive Fountain, by the said Opiatick Particles: Hence also an unwonted Languor and Slothfulness comes up∣on

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all the Members and Limbs. Hence also Opiates take away Convulsions. And from hence the Visce∣ra being before provoked (into excretory Convulsions) by Vomit or Stool, or Ve∣hemecy of Pain, as in the Cholick or Gravel and Stone in the Reins or Bladder, find their Analesia or Cessa∣tion of Pain: For whilst a plentiful Afflux and Supple∣ment of Spirits are want∣ing in the part afflicted, the few remaining can be no longer tumultuous and an∣gry; but rather lie at qui∣et, that they may subsist and maintain themselves. So also in the Scorbutick Cholick, Opiates seem as it were a certain kind of Ex∣orcism: They also bring cer∣tain ease in the Gout and Stone, whether in the Reins or Bladder as aforesaid. In Gout Pains, they have been an egregious, and as it were a Divine Succor; and have given Ease when all other things have failed, yea, where the Disease has been incurable. In this case, I have persuaded some to the constant use of this Panacaea, to wit, Landanum, which they have done with great comfort of Life, and with∣out the least hurt, although they increased its Dose by degrees to a very great quan∣tity.

23. Now afterwards, when the Sulpburous Par∣ticles of the Opiate are scat∣tered or blown away, the stock of Spirits within the 〈 in non-Latin alphabet 〉〈 in non-Latin alphabet 〉, and their Emana∣tion from thence on the Nervous parts is renewed, so that they may descend a∣gain to the parts afflicted in a full Stream, and fill full again their Fibres: Forth∣with by reason of the Spi∣rits being again accumulated and stirred up as before, the same Convulsions or Pains return. And without doubt, by this means, and accord∣ing to these reasons now assigned do Opiates quiet the strongest pains, and procure an Analesia or Indolency, with, or without Sleep, for some determinate time, as afore-mentioned.

24. How Opiates help the Irregularities of the mo∣tive

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faculty, we now come to declare. These Irregula∣rities have chiefly a respect to the Praecordia and Visce∣ra. To the First, ought to be referred the Pulse and Breathing; To the Later, Excretory Convulsions. When the Motions of the Heart and Lungs in Fevers, is so rapid, as to hasten vehe∣mently the Circulation of of the Blood; it is then hurt both as to its Accensi∣on, and depraved as to its Crasis, in that it cannot se∣perate its Superfluities and Filth, for want of a perfect Concoction. In this case Opiates break the Impetuosi∣ty of this motion, where∣by the intense Heat is lessen∣ed, from whence the Cir∣culation is gently and tem∣perately performed; and they also loosen the Blood in its joynting, whereby it sends forth its Serum and Defilements both by Sweat and Urine.

25. How Opiates quiet this motion of the Heart, we have already above plain∣ly enough declared, to wit, by depressing the Action of the Pulse: For that the O∣piatick particles do some∣what stop the Springs of the Animal Spirits in the Cerebellum, and diminish their Emanation or Efflux, from thence destinated to the nervous Praecordia, which if it should happen to be too much (from too large a Dose of the Optate) then follows a great Dejection of the Vital Faculties, and sometimes Death it self.

26. Not in a much dif∣fering manner do Opiates quiet the too vehement Mo∣tion of the Lungs, to wit, by regulating the Inordina∣tions of the Respiration or Breathing, whether it be in∣terrupted, convulsive, or otherwise disturbed. They help above all things in a vehement and continual Cough. In Asthmatick Pa∣roxysms (where the Sick seems to be in the very Agony of Death it self;) a fit Dose of an Opiate ren∣ders (as it were) unexpect∣edly all things presently se∣rene and quiet. In a Pleu∣risy also, (chiefly in its beginning) they exert their

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Power in full as large a mea∣sure.

27 The reason whereof is, that forasmuch as in these kinds of Affections, troubling chiefly the Vital parts, the Spirits dwelling in them being highly irrita∣ted, break forth into vehe∣ment and cruel Excande∣scencies, where, by their violent Motions, they disturb and invert all things; the Opiate being now taken, its Narcotick Sulphur beginning to act, immediately draws away the Succors of those raving Spirits, and forth∣with stops the Afflux of new; whereby they being in a manner extenua∣ted, and without fresh Sup∣ply, lay down their Inordi∣nations.

28. How Opiates help the immoderate or convul∣sive Motions of the Viseera, to wit, of the Ventricle and Intestines, chiefly in horrid Vomitings, and dysenterick or violent Purgings, is now our present Task: For that these Affections can scarce∣ly be cured without the use of Opiates. Now Opiates perform not these things by fixing the fervescent and corrosive Humors of the Party; but partly by stupi∣fying the Nervous Fibres by a mere Contact, where∣by the Spirits implanted within the Cavities of the Viscera, are, as it were be∣nummed; and partly by suppressing the Efflux of Spirits within the Cerebel∣lum to those parts; where∣by, becoming destitute of help and supplies, they forthwith lay aside their Convulsive Excandescen∣cies.

29. In the Blood and Humors, Opiates have an apparent Operation in Ca∣tarrhs and Defluxions of e∣very kind, we fly often∣times to these, as to the last refuge; they strongly stay Bloody Excretions, also re∣strain the serous, when they are excessive, and colliqua∣tive or melting; or reduce their Inordinations; they repress the immoderate E∣bullition of the Blood grow∣ing Feverish, and lessen its too great Inflammation. Lastly, they happily stop all

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Fluxes arising from what cause soever, and induce an Halcyon or most calme State to the Blood however di∣sturbed.

30. How these sorts of Effects are for the most part produced, we have already hinted, to wit, through the mediating affections of the Animal Spirits: For the Nervous Fibres being inor∣dinately contracted, do agi∣tate the Blood and Humors, compelling them into di∣v••••s Fluctuations and Dis∣orders; which being taken away by the Exhibition of Opiates, they presently be∣come smooth and quiet. But yet it seems, that they operate also another way; For the Opiatick Particles being poured into the Blood, do cause certain Alterations as to its Liquor, by their mere Syncrasie or Com∣mixion: For (as we said before) they are altogether untameable, and immiscible, and Heterogenous to the Blood; yet they are not E∣nemies to it, nor injurious to its Liquor.

31. And therefore Opiates may be accounted as it were Alexiterians of the same sort, which being confused with the Blood, do suddenly, and as it were in a Trice, and almost untouched, pass through its Mass; and by opening all the Holes and Pores in the passage of the Sulpburous Particles, make a free and open Passage for the Serum (in a kind of plea∣sing Sweat) whereby the said Serum and other Super∣fluities, or Malignities close∣ly bound or shut up, go forth of themselves, or else by the said Sulphurous Par∣ticles are driven out before them.

32. Hence it appears, that Opium is not altogether un∣deservedly (as an Alexiphar∣macon) put into the Com∣positions of the greatest An∣tidotes, as of Diascordium, Mithridate, and Venice Trea∣cle. Moreover, 'tis a Sign, that the Particles of Opiates, are presently (after taken) carried into the Blood, and swiftly pass through its Mass; For that they are so suddenly carried to the 〈 in non-Latin alphabet 〉〈 in non-Latin alphabet 〉, and so procure Sleep and Ease.

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33. Also it appears by common Experience, that Opiates procure Sweat and Urine, which also are ac∣coundated as some of their particular Vertues: whereby it is clear, that their Particles are not ve∣nemous to the Blood, but rather Alexiterian or resist∣ing Poyson, which is also more manifest from hence, for that Laudanum is often∣times administred with great Success in the Small Pox, malignant Fevers, yea, the Plague it self; as also in se∣veral other Diseases. In which cases, or in any o∣ther, we see not those qua∣lities which some ascribe thereto, of fixing and thick∣ening the Blood, unless by unlocking its joyntings, it causes its Serosities to be plentifully separated and sent away by Sweat and U∣rine, whereby it may be said to become thicker and more compact.

34. We have little more to say concerning Opiates in general, save to give you a few Cautions in their Ex∣hibition. Before an Opiate is given, you ought to con∣sider, First, the Constituti∣on of the Sick. Secondly, the Kind or Quality of the Disease. Thirdly, the State of the Animal Spirits, in respect both to the Animal and Vital Faculties. Fourth∣ly, the State or Condition of the Blood and Humors.

35. First, As to the Con∣stitution, or Temperament of the Patient, see that the habit of the Body, Indispo∣sition, Custome, or kind of Living do not forbid their Use. You may give them to such as are of a mo∣derate Stature, strong, or firm Body, well set, have a hot Blood, are commonly so∣luble in their Bellies, and have a quick or lively As∣pect; and much more se∣curely, if they have been be∣fore accustomed to use them. But they ought to be forbid den to such as are too fat, or too lean, have a cold Tem∣perament, soft and flaccid Flesh, have a rare Texture of Body, and Spirits easily dissipable, and for the most part bound in their Bodies, and are of a sleepy, dull, and

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sluggish Nature; and more especially, if they never had taken an Opiate be∣fore.

36. Secondly, As to the Kind or Quality of the Dis∣ease, Opiates ought to be interdicted in all the more light Affections, and in the Palsie, Vertigo, Incubus, Apoplexy, Orthopnea, (or straitness of the Lights) Dropsie of the Breast, As∣cites, Stupor, (or trembling of the Members) and in ve∣ry malignant Fevers, in the Paroxysms of intermitting Fevers, and in the Crises of other Fevers: Also in the Asthma, and other Disaffe∣ctions of the Thorax, Op∣pression of the Lungs, in Hysterick and other convul∣sive Passions, you are to give them rarely, and not without great Caution and Consideration. But in ve∣hement Head-achs, Catarrhs, Cholicks, Fluxes, the Pleu∣risy, ordinary Fevers, in Vomiting, Dysentery, Ne∣phritick Paroxisms, in Gouts, Stitches of the Side, and all kind of Pains, Opiates may be lawfully exhibited, as the only, and as it were Di∣vine Panacaea.

37. Thirdly, As to the state of the Animal Spirits, Optates are not to be given when they are already few, or oppressed, or do not e∣nough expand themselves; or whilst the Animal Facul∣ties, as to the Senses, are not very vigorous, or do not enough exert themselves; or when the Pulse and Re∣spiration are by turns reci∣procally weak, or are stop∣ped, or unequal, or more quick or slow than usual; or if a Stupor, or Enerva∣tion, with unaccustomed Languishing, possesses the extream and motive parts. But if any vehement and painful Disease afflict; if the Animal Spirits in all their Dominions are robust and strong: or are also too much expanded, or enlarg∣ed, or carried forth above measure; or lastly, that they become fierce and unruly, Optates may be safely made use of, with the hopes of exceeding good Suc∣cess.

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38. Fourthly, as to the State of the Blood and Hu∣mors; and first as to the Blood, which we are to consider in respect to its Quantity or its Quality: As to the Quantity of the Blood, Opiates ought not to be given in a Plethora (if there be such a thing which we intend in another place largely to discuss:) whilst the Blood is turging and boyling up, as in a Fe∣ver, greatly distending the Vessels, by which its Cir∣culation is swiftly repeated, lest it should any where stgnate or overflow.

39. Nor ought they to be given where there is a defect or want of Blood, as after large Blood lettings, great Haemorrhages, long Fastings, or continual Sick∣ness. In these cases the Heart endeavors its quick Circumagitation, working with a very quick and nim∣ble Pulse, as it were with double endeavors, lest that its Fluor should be broken off, and so cease. What hurt then may Opiates do here, which put a Remora, or Stop to this working of the Heart (so needful to the Life of the Sick) as is apparent from their making the Pulse dull or slow, or totally stopping of it. And for this reason it seems to be, that Sleep is forbidden persons who have been new∣ly let Blood; and that Sleep also is forbidden to Wo∣men presently after Delive∣ry, whilst the Lochia are flowing, lst the Spirits in the time of Sleep, being cal∣led back, should leave the Heart, by which it drives about the diminished River of the Blood.

40. The Quality, Crasis, or Disposition of the Blood being hurt, forbids the use of Opiates: For being stuft with Recrements or Super∣sluities, as in a Cacochymia, Dropsy, &c. it ought to be more swiftly circulated, that the Heterogenous Par∣ticles might be overcome, and quickly expelled: This Narcoicks hinder by stop∣ping the endeavor of the Praecordia, (manifest in the diminution of the Pulse) whereby the Lustration or

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Circulation of the Blood, is either frustrated or retarded. But if they be giv'n in so large a Dose as to cause Sweat, this later Operation makes some amends for the hurt of the former, because many of the said Heterogenous Particles are driven out through the Pores of the Flesh and Skin.

41. Lastly, as to the Re∣crementitious Humors accu∣mulated within the Stomach or Guts, Opiates ought not to be given, till they are carried off, or purged out, either by Vomit or Stool: otherwise being fixed there, they will stick the more strongly; for that the sple∣netick Fibres, being, as it were, stupified, are not ir∣ritated as before, nor easily, or lively perform the excre∣tory Convulsions, for the expelling those superfluous Humors; wherefore (accord∣ing to the old rule (super∣fluous humors (if any) are first to be evacuated, before the Administration of Opiates.

42. We will only give you one memorable History of an Opiatick Cure, from that Learned Man, and so conclude this Theory. Some time past (saith he) I was advised with concerning a Gentleman very Cacochy∣mick, or full of evil Humors, and miserably vexed with Nocturnal Pains, arising from the Venereal Disease, being not, or not well cured. I prescribed many things, but in vain; because very much abhorring Medicines, he would yield to take no∣thing almost besides a Dose of Laudanum. Shortly he became Hydropical from an Ascites and an Anasarca: He swelled so much, that he could scarce move from one side to the other without the help of Servants. In this Condition, I being at length sent for, and finding him obstinate, because of his before taken Medica∣ments: I made a Progno∣stick, that he was not far from Death; and that it was certainly to be expected; therefore he should prepare himself and his Affairs for Eternity. He not much di∣sturbed, earnestly asked, that for his more easy dying, he might take our Lauda∣num;

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(before, but sparingly permitted him) at his plea¦sure) or at the least in the Evening. Granting it, with a certain Admonition, I left him, and gave him, as I thought, the last Farewel, Afterwards he took that Me∣dicine daily, and daily in∣creased its Dose; so that in a short time, he had taken an incredible quantity of it. By the use of this only Medicine, he grew better every day; and within a Month space, was so well, that being free from all Humors and Pains, he had got a Stomach, and went abroad. By the assiduous use of this Opiate, his Thirst before troubling him went away; and be∣ing every night put into a great Sweat, he also made plenty of Urine.

43. Hitherto of the The∣oretick part of our Opiology; the Practick follows; the which we will exactly de∣lincate, according to the various Classes of the famous Johannes Daniel Horstius, in his Pharmacopaeia Galeno-Chymica Catholica Specialis, lib. 13. pag. 369. After which we will give you the exact Recipe of Guttae Vitae nostrae, or our Drops of Life according to their two-fold manner of Preparation; which Medicine is now fa∣mously known throughout the three Kingdoms for its manifold and adminable Vertues.

Examples in Compounding Opiates.
I. In Affects of the Head.

44. ℞ LAudanum of Pa∣racelsus gr. iij. iv. v. or 6. Sweet Maj rm Water ℥ss. Syrrup of Beto∣n ʒij. Consect of Emerals ℈j. Oyl of Pearls gut iij. Oyl of Fennel Seed gut. j. Spirit of Vitriol, q. s. or to make it gratefully four, mix and make a draught for one Dose.

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45. ℞ Laudanum of Pa∣racelsus what you please; or gr. v. Syrup of the Juice of Black Cherries, Vervain Water, Nutmeg Water, A. ʒij. Confect of Jacynths ℈j. Salt of red Coral gr. iij. Oyl of White Amber gut. j. mix, and make a draught for one Dose.

46. ℞ Waters of Wild Poppies, of Cowslips, A. ℥vj Syrup of Poppies ℥ij. Sal Prunellae ʒss. mix them, Dose ℥iij. or iv. thrice a day, in watching without a Fever, or any manifest Cause, and in a Pleuri∣sie.

47. ℞ Poppy Water, ab ʒiv. ad vj. Syrup of Pop∣pies ʒj. give it twice or thrice a day for the same purpose.

48. ℞ Diacodium, a ʒiv. ad vj. Cowslip Water ℥iij. Treacle Water ʒiij. mix, and make a Poti on.

49. ℞ Gascoyn's Powder, ℈j. Diacodium ʒiij. Diascor dium ℈ij. mix them in a Spoon, and so take it.

50. ℞ Carduus Water ℥iij. Diacodium ℥ss. Spirit of Harts-horn gut. xvj. or xx. mix, and make a Draught, to provoke Sleep and Sweat.

51. ℞ Laudanum Para∣celsi gr. ij. or iij. Treacle Water ℥j. Cowslip Wa∣ter ℥ij. dissolve the Lauda∣num in the Waters, and make a Draught.

52. ℞ Laudanum Para∣celsi q. s. Magistery of Pearls, Emeralds prepared A.gr. iij. mix, and with Oyl of Fen∣nel Seed, make little Pills to be gilded for one Dose.

53 ℞ Landanum q. s. Magistery of red Coral, Ja∣cynthus prepared A. gr. iij. mix, and with Oyl of White Amber, or Oyl of sweet Marjoram, make Pills for one Dose.

54. ℞ Laudanum q. s. Conserve of Marjoram ʒj. Confect of Emeralds ℈j. Species Diambrae ℈ss. Elaeo∣saccharum Cinnamomi, so much as may make a Bolus for one Dose.

55. ℞ Laudanum q. s. Conserve of Rosemary Flowers ʒj. Confect of Ja∣cynthus

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℈j. Species Diamoschi dulc. ℈ss. Oyl of Mace gut. j. Sugar tabulated and pearled q. s. mix, and make a Bolus for one Dose.

II. In Affections of the Heart.

56. ℞ LAudanum q. s. Syrup of Li∣mons ʒij. Waters of Bo∣rage, of Cinnamon, of Ro∣ses, of Water Lillies A. ʒj. Confectio Alkermes, Tincture of Coral, A. ℈ss. Salt of Pearls gr. iij. mix, and make a draught for one Dose.

57. ℞ Laudanum q. s. Syrup of Juice of Citrons, and Rasberries A, ʒij. Wa∣ters of Bawm and Bugloss A. ʒjss. Confect of the pre∣cious Stones ℈j. Tincture of the Ruby or Carbuncle ℈ss. mix, and make a draught for one Dose.

58. ℞ London Landanum gr. j. or ij. Compound of Powder of Crabs Claws, from ℈ss. ad ℈j. Syrup of Cloves q. s. make iij. Pills to be taken going to rest.

59. ℞. Laudanum q. s. Pearls trochiscated, Bone of a Stag's Heart, A. gr. iij. mix, and with Oyl of Mace, make little Pills to be gild∣ed for one Dose.

60. ℞ Laudanum q. s. the five pretious Stones prepared, Oriental Bezoar, A. gr. j. mix, and with Oyl of Cinnamon, make small Pills to be gilded for one Dose.

61. ℞ Laudanum gr. j. or ij. Stomach Pills cum Gum∣mi ʒss. make iv. Pills to be taken going to Sleep: it chears and revives the Heart, and is prevalent against the Cholick.

62. ℞ Laudanum gr. j. or ij. Diascordium ℈i. make a Bolus: you may also add Confect of Alchermes, or de Hacyntho ℈ss.

63. ℞ Laudanum q. s. Conserve of Borrage vitrio∣lated ʒj. Confectio Alkermes ℈j. Species Diamargar. fri∣gid. ℈ss. Sugar tabulated and pearled, q. s. mix, and make a Bolus for one Dose.

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64. ℞ Romani Philonum, a ℈j. ad ℈ij. Conserve of Cloves ʒss. mix them and make a Bolus to be taken going to rest. It is good also against the Cholick in a cold Temperament.

65. ℞ Laudanum q. s. Conserve of Clove Gilli∣flowers vitriolated ʒj. Con∣fect of Citron Peels ℈j. Species Diarrhodon Abbatis ℈ss. Elaeosaccharum Cinna∣momi, so much as may make a Bolus for one Dose.

III. In the Epilepsia, Vertigo, &c.

66. ℞ LAudanum q. s. Syrup of Peony Flowers, Water of Lilly Convally, Aqua Epileptica, A. ʒij. Conserva Cephalica ℈j. Chymical Oyls of Cubebs, and of Elks Hoof, A. gut. j. Spirit of Vitriol q. s. mix, and make a Draught for one Dose.

67. ℞ Laudanum q. s. Syrup of Betony, Waters of Lavender, and of the Flow∣ers of the Tile Tree, A. ʒij. Confect of Emeralds ℈j. Essence of Camphir gr. iij. Oyls of White Amber, and of Harts Horn, A. gut. j. Elixir of Peony q. s. mix them, and make a Draught for one Dose.

68. ℞ Laudanum q. s. Magistery of Man's Skull, Sulphur of Luna dryed, A. gr. iij. mix, and with Oyl of of Elks Hoof, make little Pills, which gild for one Dose.

69, ℞ Laudanum q. s. Ʋnicorns Horn, Magistery of Coral, A. gr. iij. mix, and with Oyl of Man's Skull, make little Pills to be gil∣ded, for one Dose.

70. ℞ Laudanum q. s. Conserve of Peony Flowers vitriolated ʒj. Confect of E∣meralds ℈j. Species Dialunae Mynsichti ℈ss. Oyl of Rose∣mary gut. j. mi. and with Species Diambrae q. s. make a Bolus for one Dose.

71. ℞ Laudanum q. s. Conserve of Rosemary flow∣ers ʒj. Cephalick Conserve, Species Dialunae, A. ℈j. Oyl of Lavender, gut. j. mix, and with Species Diamoschu dulce q. s. make a Bolus for j. Dose.

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IV. In Vomiting, Hiccough, and debility of the Stomach.

72 ℞ LAudanum q. s. Syrup of Mint. Stmach water, A. ʒiij. ex∣tract of Calamus Aromati∣cus, Salt of Wormwood, A. gr. iv. Oyls of Nutmegs and of Mastich, A. gut. j. Elixir of Vitriol q. s. ad gratiam, mix for one Dose.

73. ℞ Laudanum q. s. Syrup of Quinces, water of Calamus Aromaticus, A. ʒiij. Extract of Galangal the less, Niter vitriolated, A. gr. iv. Oyls of Cloves and Spear-mint, A. gut. j. Elix∣ir of Sulphur, q. s. ad gra∣tiam; mix, and make a draught for a Dose.

74. ℞ Laudanum q. s. Sp••••ies Diagalangae ℈ss. mix. and with Oyl of Sage, make shall Pills for one Dose, which are to be gilded.

75. ℞ Laudanum q. s. A∣romaticum Caryophillatum ℈ss. with Oyl of Worm∣wood make small Pills, for one Dose to be gild∣ed.

76. ℞ Laudanum q. s. green Ginger preserved ʒj. Roots of Acorus condited ʒss. Oyls of Mastick and Ze∣doary, A. gut. j. mix, and with Species Diagalangae, make a Bolns for one Dose.

77. ℞ Laudanum q. s. Conserve of Spear-mint ʒj. Quiddony of Quinces ʒss. Oyls of Cinnamon, and of Calamus Aromaticus, A. gut. j. mix, and with Aromatcum Caryophillatum, make a Bolus for one Dose.

V. In Mlancholly, Madness, Frenzy, &c.

78. ℞ LAudanum q. s. Alexandrian Ju∣••••••, 〈…〉〈…〉 Water, A. ʒiij. 〈…〉〈…〉 E••••••••••, A. ℈j. Elixir Proprietatis, made with Oyl of Sulphur q. s. d geatram, mix, and make 〈◊〉〈◊〉 draught for one Dose.

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79. ℞ Laudanum q. s. Bawm water ℥ss. Syrup of Bugloss ʒij. Confect of Ci∣tron Peels, ʒss. Essence of Saffron gr. iv. Tincture of Emeralds ℈ss. mix for one Dose.

80. ℞ Laudanum q.s. Sul∣phur of Luna dried, Magi∣stery of Pearls, A. gr. iij. mix, and with Chymical Oyl of Roses, make little Pills to be gilded for one Dose.

81. ℞ Laudanum q. s. Pouder of Tortoise Shell burnt, Magistery of red Co∣ral, A. gr. iij. mix, and with Oyl of Cinnamon make small Pills to be gil∣ded for one Dose.

82. R. Laudanum q. s. Confect of Hyacinths ʒj. Essence of Hypericon ℈j. Spe∣cies Diamargariton frigidum, Elaeosaccharum Ctri, A. ℈ss. mix, and with Sugar tabu∣lated and pearled q. s. make a Bolus for one Dose.

83. R. Laudanum q. s. Confect of Emeralds ʒj. Essence of Hypericon ℈j. Tincture of Coral, Elaeosac∣charum Cinnamomi, A. ℈ss. mix, and with Spicies Diar∣rhodon Abbatis, make a Bolus for one Dose.

VI. In all kinds of Fevers.

84. R. Laudanum q. s. Carduus Water ℥j. Syrup of Centaury the less ʒij. Sal Febrile Mynsichti ℈j. Ex∣tract of Zedoary ℈ss. mix, and make a draught for one Dose.

85. R. Laudanum q. s. Aquae Febrifugae ℥j. Syrup of Wormwood ʒij. Elixir Febrile ℈j. Extract of Cloves ℈ss. mix, and make a draught for one Dose.

86. R. Laudanum q. s. Sal Febrile ℈ss. mix, and with Oyl of Wormwood, mix, and make small Pills to be gilded for one Dose.

87. R. Laudanum q. s. Niter vitriolated ℈ss. mix, and with Oyl of Camphir, make little Pills, to be gil∣ded for one Dose.

88. R. Laudanum q. s. Venice Treacle ʒj. green

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Ginger preserved ʒss. Spe∣cies febrifuge, ℈j. Salt of Wormwood, Elaeosaccbarum Myrrhae, A. ℈ss. mix, and with Species Diarrhodon Ab∣batis, make a Bolus for one Dose.

89. R. Laudanum q. s. Venice Treacle ʒj. Colamus Aromaticus condited ʒss. Sal Febrile Mynsichti ℈j. E∣laeosaccharum Rutae; mix, and with Species Diarrho∣don Abbatis, make a Bolus for one Dose.

VII. In Diseases of the Breast, Coughs, Asthma's, Phthisicks, &c.

90 ℞ LAudanum q. s. Syrup of Li∣quorise, Syrup of Horehoud, A. ʒjss. waters of Lohoch sanum, of Hyssop, of Fennel, A. ʒj. Elaeosaccharum Anisi ℈ss. mix, and make a draught for one Dose.

91. ℞ Laudanum q. s. Waters of Horchound, of Coltsfooot, of Pauls Beto∣ny, A. ʒiss. Syrup of Hys∣sop, Syrup of Jujubies, A. ʒj. Rob. nucum ʒss. Elaeosac∣charum Faeniculi ℈ss. mix, and make a Draught for i. Dose.

92. ℞. Diacodium ℥iij. Snail water ℥i. mix them: It is good in Cough and Phthisick: Dose one spoon∣ful at going to Bed, and ano∣ther at Midnight, if need be.

93. ℞ Laud. q.s. flowers of Sulphur compound, flowers of Ben. A. gr. iv. mix, & with chymical Oyl of Sage, make Pills, which gild for i. dose.

94. ℞ Laudanum q. s. Lac sulphuris, Gum Traga∣canth, A. gr. iv. mix, and with Chymical Oyl of Ca∣momil, make Pills, which gild for one Dose.

95. ℞ Pills of Styrax, gr. v. or vi. Lac Sulphuri ℈ss. Oyl of Anniseeds gut. j. Balsam of Peru, enough to make all into iij. Pills, for Coughs, Asthma's, &c.

96. ℞ Pills of Hounds∣tongue gr. vj. or viij. Laud. gr. j. Lac Sulphuris ℈ss. mix, and make Pills for the same Intentions.

97. ℞ Laudanum q. s. Pectoral Lozenges ʒj. Lo∣hoch sanum ʒss. Juice of Li∣quorice, Elaeosaccharum Fae∣niculi, A. ℈ss. Extract of

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Saffron gr. iij. mix, and with Mithridate q.s. make a Bolus for one Dose.

98. ℞ Laudanum q. s. Conserve of Violets ʒj. Lo∣hoch de pino ʒss. Species Diasulphuris Mynsichti ℈j. Extract of Elecampane, Elaeosaccharum Anisi A. ℈ss mix, and with simple tabu∣lated Sugar q. s. make a Bo∣lus for one Dose.

99. ℞ Extract of Opium ℈j. and of Saffron ʒj. Es∣sence of Coral ʒiiss. Oyls of Nutmegs, of sweet Mar∣joram, of Aniseeds, A. ℈ii. Oyl of Amber ℈i. mix them: Dose gr. iij. or iv.

100. Extracts of Pill. de Cynoglosso ʒ j. of Philonum Romanum, and of Venice Treacle, A. ʒi. Ambergrise, Musk, Saffron, A. ℈ss. Bezoar Stone, Ʋnicorns Horn, A.gr.vi. with Oyl of Cloves, make Laudanum: Dose gr. iii. or iv.

VIII. In stopping all Defluxions of Humors, and thin Catarrhs falling from the Head upon the Aspera Arteria, causing perpetual Coughings, and want of Sleep and Rest.

101. ℞ LAudanum q. s. waters of green Walnuts, and of Scabious, A. ʒii. Syrup of Corn Pop∣pies, ʒiss. Rob. Nucum ʒj. Magistery of Coral rosate, Elaeosaccharum Nucis mos∣chatae, A. ℈ss. mix, and make a draught for one Dose.

102. ℞ Laudanum q. s. Mynsichts, blessed Water of Time ℥iij. Syrup of Jujubies ℥ij. Diacodium Crocatum ℥j. Elaeosaccharum of Cubebs ℈ss. mix for one Dose.

103. Another in a very hot Cause.Laudanum q. s. Pomgranate Wine ℥j. Rose water ʒij. Syrup of Poppies, Diamorum, A. ʒiss. Niter vitriolate gr. ij. mix for one Dose.

104. ℞ Laudanum q. s. Magistery of Gum Sanda∣rarca, Emeralds prepared, A. gr. iv. mix, and with Oyl of Mastich make little Pills, to be gilded for one Dose.

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105. ℞ Laudanum q. s. Magistery of Mastich, white Amber prepared, A. gr. iv. with Oyl of Frankincense, make little Pills to be gild∣ed for one Dose.

106. ℞ Species Diambrae compleat ℥ii. Thebian Opium ʒvj. Mummy ʒss. Juice of Hemlock ℥j. red Coral, white Amber prepared, A. ℈ij. Saffron ℈j. Musk gr. xv. Ambergrise gr. xij. with S. V. five times rectified, make an Extract according to Art. Dose à gr. ij. ad iv, vj. or more, Strength and Custom considered.

107. ℞ Species Diambrae, ℥ss infuse fourteen days in S. V. after add Opium, Juice of Henbane, A. ʒij. red Coral, Amber prepared, A. ℈ss. Myrrh gr. viij. Saffron gr. v. Musk gr. iv. affuse the Spi∣rit again and digest for a Month, then evaporate the S. V. till it is fit to make Pills. Dose à gr. ij. ad x. Camer trius.

108. ℞ Opium extract∣ed ʒj. Juices of Oranges and Citrons, A. ʒss. Cin∣namon. Cloves, A. ʒss. mix, and digest in the Sun, or in a warm Sand Heat, for a Month, then add Saf∣fron ʒss. Liquor of Coral, Magistery of Pearls, A. ℈j. Musk ℈ss. Ambergrise gr. v. mix, digest again for a month; then add Quintes∣sence of Gold ℈j. and keep it for use. Dose à gr. ij. ad viij.

109. ℞. Opium extract∣ed ℥vj. Juice of Henbane inspissate ℥ii. which Ex∣tract also with S. V. Saffron ʒiiss. white Amber, ʒii. Oyl of Nutmegs by expres∣sion, red Coral prepared, A. ʒiss. Leaves of Gold, Musk, A. ℈i. Mummy ℈ss. Oyl of Nutmegs Chymical, gut, xxiv. Oyl of Aniseeds, gut xii. mix, and make Pills. Dose à gr. ii. ad vi. Bani∣ster.

110. ℞ Opium, Species Diambrae, A. ℥j. make an Extract with S. V. to which add Extract of Juice of Henbane ʒvi. Extracts of Mummy, of Castorum, A. ʒ. of Frankincense ʒss. of Sassron ʒii. Essences of Co∣ral and Pearl, A. ℈i. Oyls chymical of Cinnamon ʒss. of Amber, of Citrons, of

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Cloves, of Mace, of Nutmegs, of Aniseeds, Ambergr. Musk. A. ℈ss. mix, and make a Mass. Dose à gr. ij. ad viij.

111. ℞ Extracts of Opium, of Henbane Juice, or Species Diambrae, A. ℥j. to which add white Amber, red Co∣ral prepared, A. ℈ij. extract of Saffron ℈j. Musk gr. xvj. Ambergrise gr. x. mix, and make a Mass for Pills. Dose a gr. i. ad vj. Brunne∣rus.

112. ℞ Juice of Citrons clarify'd, & strain'd through Hippocrates his Sleeve ℥ss. Thebian Opium extracted with S. V. to the thickness of Honey ʒiv. mix them well, then add Magisteries of Pearl and Corals, A. ʒij. Oyl of Cinnamon ʒss. Oyl of Cloves ℈ss. mix, and keep them for use: It is a neat Composition. Dose a gr. iij. ad vi. viij. x. or xij. Felix Wurtz.

113 ℞ Opium extract∣ed ʒvi. extract of Speeies Diambrae ℥ij. extract of Henbane Juice ʒj. extract of Mummy ʒss. extract of Saffron ℈j. red Coral, white Amber prepared, A. ℈ij. Musk gr. xvij. Ambergrise gr. xij. mix them well. Dose a gr. ij. ad x. Wie∣rus.

114. ℞ Extract of O∣pium, Magisteries of Pearl and Coral, A. ʒj. extract of Saffron ʒij. Oyl of Cloves ℈j. mix them well. Dose a gr. j. ad vi. Finki∣us.

115 ℞ Laudanum q. s. conserve of scabious Flow∣ers ʒj. Lohoch de papavere ʒss. Species Diaireos simple, ℈j. and with Diacodium soli∣dum, make a Bolus for one Dose.

116 ℞ Laudanum q. s. conserve of Corn Poppy Flowers ʒj. Rob. of Cornel berries ʒss. Species Diamar∣gariton frigidum ℈j. mix, and with Sugar Penids, make a Bolus for one Dose.

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IX. In all Fluxes of the Bowels, as Diarhaea's, Dysen∣teria's, and Lienteria's.

117 ℞ LAudanum q. s. Tormentil wa∣ter ℥ss. Syrupus Hemoptoicus, ʒij. Essence of the Flowers of Archangel, or dead Net∣tles, extract of Bistort root, Elaeosaccharum of Nutmegs, A. ℈ss. mix, and make a draught for one Dose.

118 ℞. Laudanum q. s. Plantane Water ℥ss. syrup of Quinces ʒij. Essence of Balaustians ℈i. extract of Tormentil, Elaeosaccharum of Cloves, A. ℈ss. mix, and make a draught for one Dose.

119. ℞ Laudanum Cy∣doniatum liquid. gut. xv. ad xx. Cinnamon Water ℥j. mix them for one Dose: It is good in Dysenteries, and all manner of Gripings of the Guts, as from Wind, &c.

120 ℞ Laudanum Cy∣nodiatum, Venice Treacle, Confectio Hamech, A. ʒij. Pow∣der of red Cloath ʒj. con∣serve of red Roses ℥j. Syrup of Coral enough to make a Confection. Dose ʒj. every fourth and fifth hour, in ve∣ry bloody Dysenteries with with pains.

121. ℞ Laudanum q. s. Magistery of Coral rosate, crocus martis, A. gr. iv. mix, and with Oyl of Mastich, make little pills, to be gild∣ed for one dose.

122. ℞ Laudanum q. s. Magistery of Gum Arabick, Harts-horn burnt and pre∣pared, gr. iv. mix, and with oyl of Sage, make little pills for one Dose.

123. ℞ Laudanum q. s. old Conserve of Roses ʒj. Narcotick Sulphur of Vitri∣ol ℈j. Species Diamartis, Elaeosaccharum of Orange peels, A. ℈ss. mix, and with species Diarhedon abba∣tis, q. s. make a Bolus for one Dose.

124. ℞ Laudanum q. s. conserve of Comfrey Flow∣ers ʒj. fine Bole ℈j. species Diagalangae, Elaeosaccharum Citri, A. ℈ss. mix, and with Diamargariton frigidum, make a Bolus for one Dose.

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X. In Bloody Excretions, Hemorrhages, Overflowings of the Terms, Hemorhoides, &c.

125 ℞ BRasil Wood ground M. j. Gum Arabick ʒiij. White wine q. s. boyl all in a Diet-pot, strain and add to ℥j. thereof Laudanum q. s. Syrup of Quinces, Diacodi∣um Crocatum, A. ʒij. magi∣stery of Coral rosate, Essence of Crocus martis, A. ℈ss. E∣laeosaccharum of Cloves gr. iv. Rob. of Barberries e∣nough to make it pleasant; mix, and make a draught for one Dose.

126. ℞ Roots of Tor∣mentil, Virginia Snakeroot, Roots of Succory, A. ʒj. Harts-horn rasped, Threads in the middle of blown Ro∣ses, Seeds of Plantane and Sorrel, A. ℥ss. Leaves of Shep∣herds purse, of golden Li∣verwort, of Burnet, A. ℈i. Flowers of Yarrow, red Ro∣ses, of Rosemary, A. ℈j. Sebestins No. ij. Boyl in a Diploma or Diet Pot, with a sufficient quantity of stip∣tick red Wine: strain, and to the straining ℥jss. add, Laudanum q. s. Syrups of Corn-poppies, of Comfrey, A. ʒij. Essence of Dragons blood ℈j. Elaeosaccharum of Nutmegs ℈ss. Rob of Eng∣lish Currans, enough to make it pleasant; mix, and make a Draught for one dose.

127 ℞ Laudanum gr. v. water of Shepherds purse ℥jss. Rob of Elder-berries ʒiij. Sal prunellae ℈ij. ex∣trac of Tormentil ℈ss. Camphir gr. iv. mix, and make a draught for one Dose. This is an approved thing against the overflow∣ing of the Terms.

128. ℞ Laudanum q.s. fine Bole prepared, magistry of Coral rosate, A.gr.iv.mix, & with oyl of Rosemary, make Pills to be gilded for i. Dose.

129. ℞ Laudanum q. s. Moss of the Sloe or Bullies tree, magistery of Pearl ro∣sate; mix, and with Oyl of Sage, make Pills to be gilded for one dose.

130. R. Laudanum q. s. Rob. of Quinces ʒj. Troches of Spodium ℈j. Powder of

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the Cuttle-fish Bone, Elaeo∣saccharum of Zedoary, A. ℈ss. mix, and with Diamargari∣ton frigidum make a Bolus for one Dose.

131. ℞ Laudanum q. s. Comfrey roots preserved ʒj. Troches of Terra sigillata ℈j. white Amber prepared, Elae∣osaccharum of Nutmegs, A. ℈ss. mix, and make a Bolus for one Dose.

XI. In the Cholick and Illiack Passion, &c.

132 ℞ Conserve of red Roses ℥j. Ze∣doary ʒj. boyl in Camomil water ℥iiij. strain, and to the strainings ℥jss. add Laudanum gr. vj. Syrup of Oranges ʒij. Mynsicht his extract for the Cholick ℈j. Elaeosaccharum of Juniper ℈ss. mix and make a draught for one dose.

133. R. Laudanum q. s. Mynsicht's blessed Water of Time, ℥ss. Syrup of Mint ʒij. Mynsicht's Cholick ex∣tract ℈j. Elaeosaccharum of Oranges℈ss. mix for one Dose.

134, ℞ Laudanum q. s. Carminative water ℥ss. Sy∣rup of Citron peels ʒij. ex∣tract of Zedoary, Elaeosac∣charum, A. ℈ss. Spirit of Ni∣ter q. s. ad gratiam mix for one Dose.

135. ℞ Liquid Lauda∣num, made with Tincture of Salt of Tartar, gut. xx. species of Hiera ʒss. make iv. pills to be taken going to Bed, to purge and allay pains in Cholicks.

136 R. Liquid Laudanum made as aforesaid gut. xx. Aqua mirabilis, or Cinna∣mon Water ℥j. Water of Pyrethrum ℥ij. mix for Cho∣lick, Gout and Nephritick pains.

137. ℞ Laudanum q. s. magistery of the Stone of a Carps Head, anckle bone of a Hare calcined, A. gr. iv. mix, and with white oyl of Am∣ber, make Pills to be gilded for one Dose.

138. ℞ Laudanum q. s. Oriental Bezoar, anckle bone of a Hogs foot calcined, A. gr. iv. mix, and with oyl of Cummin seeds, make lit∣tle pills to be gilded for one dose.

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139. ℞ Laudanum q. s. Conserve of Mint ʒj. Cho∣lick extract ℈j. Elaeosaccha∣rum of Cinnamon ℈ss. mix, and with species Dianisi, make a Bolus for one dose.

140. ℞ Laudanum q. s. Conserve of Corn-poppy Flowers ʒj. Elaeosaccharum of Camomil ℈ss. Niter vi∣triolated gr. iv. mix, and with species Diacymini, make one dose.

141. ℞ Opium dissolved in Malago Wine ℥j. Essence of Castoreum ℥ss. extract of Aromaticum Rosatum, ex∣tract of Diambrae, extract of species Diamoschu, A. ʒj. Tincture of Saffron ℈ij. species Diamoschi ʒss. mix, and make Laudandm Spa∣gyricum in Cholica: It is given with Syrup of Stae∣chas. Dose a gr. j. ad vj. or viij. Mylius.

142. ℞ Extract of Opi∣um with S. V. ℥ss. extract of Myrrh, Essence of Castor, A. ʒj. mix them, and add to the Mass the following Extract. ℞ Seeds of Par∣sly and Smallage, A. ʒj. Styrax, black Pepper, long Pepper, Euphorbium, A. ℈j. dissolve in Mallago Wine, digest, extract, express and evaporate to a due consi∣stence, and add it to the for∣mer. Dose a gr. j. ad vj.

143. ℞ Extract of Opi∣um ʒij. Musk ℈j. mix them well, and add to the Mass the following Extract. ℞ Consect of Anacardiums ℥jss. Diacastorei, Myrrhae, A. ℥ss. Saffron, black Pepper, A. ʒij. make an extract with Spirit of Mallago Wine, and add it to the former. Dose a gr. ij. ad viij. It is famous, not only in Cholick Passi∣ons, but in Watchings and want of rest.

XII. In Pleuritick Pains, and Stitches of the Sides.

144. ℞ LAudanum q. s. Corn poppy Flower water ℥ss. Syrup of Maiden-hair ʒij. Extract of Liquorise ℈j. Elaeosaccharum of Anniseeds ℈ss. make a draught for one dose.

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145. ℞ Laudanum q. s. Water of Ladies Thistle ℥ss. Syrup of Jujubes ʒij. Es∣sence of Corn-poppy Flow∣ers, Elaeeosaccharum of Fen∣nel-seed, A. ℈ss. make a draught for one dose.

146. ℞ Laudanum q. s. Jaw-bone of a Pike, Tooth of a Bore prepared, A. gr. iv. mix, and with Oyl of Ben∣jamin, make little Pills to be gilded for one dose.

147. ℞ Laudanum q. s. Flowers of Sulphur com∣pound, of Liquorice extract∣ed, A. gr. iv. mix, and with Oyl of Hyssop, make Pills to be gilded for one Dose.

148. ℞ Laudanum q. s. Conserve of Corn-poppy Flowers ʒj. Lohoch sanum ʒss. Pleuritick species of Mynsicht ℈j. Elaeosaccharum of Cummin seeds ℈ss. mix, and with Diatragacinth. fri∣gid. make a Bolus for one Dose.

149. ℞ Laudanum q. s. Conserve of Violets ʒj. Dia∣codium Crocatum ʒss. Myn∣sicht's pleuritick spedies ℈j. Elaeosaccharum of Camomil ℈ss, mix, and with Diaire∣os simple make a Bolus.

XIII. In Nephritick and Arthritick Pains, as of Stone and Gout.

150 ℞ LAudanum q. s. Aqua Nephri∣tica ℥ss. Syrup of Marsh Mallows ʒij. Salt of Pearch Stones ℈ss. Oyl of Pearls gut. iv. mix, and make a draught for one Dose.

151. ℞ Laudanum q. s. Germander Water ℥ss. Sy∣rup of Mallows ʒij. Salt of Crabs Eyes ℈ss. Oyl of red Coral gut. iv. mix, and make a draught for i. dose.

152. ℞ Laudanum q. s. magistery of Jews Stone, Venetian Borax, A. gr. iv. mix, and with Spirit of Turpentine, form Pills to be gilded for one Dose.

153. ℞ Laudanum q. s. Magistery of Spurge Stone, Niter prepared, or Salt of Egg-shells, A. gr. iv. mix. and with Oyl of Parsly seed, make Pills, which gild for one dose.

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154. ℞ Extract of Opi∣um, Essence of Castoreum, A. ℥ss. mix well, and add thereto this following Ex∣tract. ℞ Styrax, Myrrh, Celtick Spike, A. ʒij. leaves of Roses, of Asarabacca, Bramble-berry, Schaenanth, Liquorice, A. ʒjss. Smal∣lage and Parsly seed, Winter Cherries, A. ʒj. Seeds of the White Thorn, of Marsh∣mallows, A. ʒss. bruise, in∣fuse, and with S. V. make an extract, which mix with the former, give it with Syrup of Maiden-hair, and Pills of washed Turpentine.

155. ℞ Laudanum q. s. Conserve of Violets ʒj. roots of Burnet condited ʒss. Species Dianitri Myn∣sichti ℈j. Elaeosaccharum of Parsly ℈ss. mix, and with Sugar of Violets make a Bolus.

156. ℞. Laudanum q. s. Conserve of Mallow Flow∣ers ʒj. Eringo roots condi∣ted ʒss. species Nephriticae Mynsichti ℈j. Elaeosaccharum Citri ℈ss. mix, and with sugar of Roses make a Bo∣lus.

XIV. In Watchings, Ʋnquietness annd Restlesness.

157 ℞ LAudanum q. s. Aqua Hypnoti∣ca ℥ss. Syrup of Corn pop∣py Flowers ʒij. Elaeosaccha∣rum Faeniculi ℈ss. Oyl of Pearls gut.iv. make a draught for one dose.

158. ℞ Laudanum q. s. Corn poppy Water ℥ss. Syrup of Poppies simple ʒj. Elaeosaccharum Anisi ℈ss. Spirit of Vitriol gut. iij. mix, and make a draught or one dose.

159. ℞ Laudanum q. s. Magistery of Pearl, Amber∣grise, A. gr. iv. mix, and with Oyl of Styrax Cala∣mita, make little Pills, which gild for one Dose.

160. ℞ Laudanum q. s. Magistery of red Coral, Lig∣num Aloes, A. gr. iij. mix, and with Oyl of sweet Asa or Benjamin, make little Pills, which gild for one Dose.

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161. ℞ Laudanum q. s. Conserve of red Roses vi∣triolate ʒi. Lohoch de Papa∣vere ʒss. Species Diamoschi ℈ss. extract of Saffron gr. vi. mix, and with Diarrho∣hodon abbatis, make a Bo∣lus.

162. ℞ Laudanum q. s. Conserve of Violets vitrio∣late ʒi. Diacodium Croeatum ʒss. species Diambrae ℈ss. ex∣tract of Enula gr. iv. mix, and with Diamargariton fri∣gidum make a Bolus.

163. ℞ Laudanum q. s. Laud. minerale Mynsichti gr. vi. Conserve of Corn pop∣py Flowers ʒi. Camphir, Saccharum Saturni, A. gr. iv. Castoreum, ℈ss. mix for a Bolus.

XV. In Hysterick Affections, or Diseases of the Womb.

164. ℞ SPicknard, one blade, Asarum, Indian Leaf, Orrice Root, A. ʒi. Storax, Myrrh, Saf∣fron, A. ʒii. Spirit of Ma∣lago Wine q. s. mix, digest, dissolve, and strain by Ex∣pression; to the Expression add Essence of Opium ℥ss. extract of Castorcum ℥i. Salt of Mother of Pearls ʒii. mix, and make a Laudanum dose ʒss. with Syrup of Mug wort.

165. ℞ Species Diamos∣chi, Diambrae, A. ʒii. Essence of Castor ℥ss. Essence of O∣pium ʒi. mix, and with S. V. q. s. make an Opiate. Dose ad ʒss. with Syrup of Mugwort: These two are given in pains of the Womb, where there is no Ulcer or Soreness.

166. ℞ Myrrh, Storax, Frankincense, white Starch, A. ʒii. Sarcocol, Mastich, Seeds of Endive, of white Poppy, of Plantane, A. ʒ ss. Bdellium ʒi. Opium ʒii. mix, infuse, digest and dissolve in S. V. q. s. then strain out by expression, to which add Essence of Castorcum ℥ss. Essence of Saffron ʒi. mix, and make an Opiate, to be given with Syrup of Jujubes in pains of the Womb with Ulceration.

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XVI. In Pains of the Bladder or its Neck, with, or without Ʋlceration.

167 ℞ JUice of Liquorice, Cortex Mandra∣gorae, A. ʒii. Myrrh, Storax, Mastich, Frankincense, A. ʒi. Seeds of Popples, of Endive, of Mallows, Winter-Cher∣ries, Mucilage of Gum Tra∣gacanth, of Gum Ara∣bick, A. ℈ii. dissolve in Malago Wine, and express: To the Expression add Ex∣tract of Opium ℥iss. species Diamoschi ℥i. mix, and make an Opiate to be given with Syrup of Jujubes.

168. ℞ Juice of Liquo∣rice ʒiv. Storax, Traga∣canth, Gum Arabick, white Starch, A. ʒiii. fine Bole ʒii. infuse and digest in Wine, and strain out by expression; to the straining add extract of Opium ʒii. species Diamofchi dulcis ℥i. mix, and make an Opiate ut supra.

169. ℞ Acacia, Hypocy∣stis, flesh of Quinces, Sumach, Nut Galls, A. ʒi. Cinna∣mons, Cypress, A. ʒss. mix, infuse, digest, and dissolve in Malago Wine q. s. then strain out; to the straining add extract of Opium, Ma∣gistery of red Coral, A. ʒi. mix, and make an Opiate to be given with Syrup of dried Roses: This also pre∣vails against a tedious loos∣ness, or flux of the Bow∣els.

XVII. The Preparation of Guttae Vitae nostrae, Or, our Drops of Life, which is two-fold.

170 FIrst, with Spirit of Wine filled with volatile Salt of Tartar. ℞ five Glasses holding a pretty deal more than a quart a piece; put into each a quart or better of S. V. rectified and filled with volatile Salt of Tartar (that is S. V. Drawn from new Rhenish Wine, assused on Salt of Tartar, and gently fermented) the making of which we have taught in

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Sect. 82 and 83. cap. 25. following. Into the first Glass put Thebian Opium ℥viii. dissolved in a part of the same Spirit. Into the second Glass put Saffron and Cochinele (the later in fine powder) A. ℥i. Into the third put Castoreum freed from Skins and Fat, and redu∣ced into Powder ℥ii. Into the fourth put Cloves and Nutmegs in Powder, A. ℥i. Into the fifth, put Virginia Snake-root bruised, Zedoary in gross Powder A. ℥i. digest all severally a month in a place, neither hot nor cold, shaking them twice a day: Then let the Opium stand three days without shaking, (as also the Tincture of Saffron, &c.) decant the clear Opiate Tincture into a great Glass holding about six quarts, which reserve. To the Magma of the Opi∣um put the clear decanted Tincture of Saffron, &c. shake them well together twice a day, for three days; then let the Glass stand, (as also the third Glass con∣taining the Tincture of Castor) three days without shaking; after which decant the clear Tincture of Saffron, &c. from the Opiate Magma, and put it to the Tincture of Opium in the great Glass; and to the Opiate Magma, put the clear decanted Tin∣cture of Castor; which shake well together twice a day, for three days; then let the Glass stand (as also the fourth Glass containing the Tincture of Cloves, &c.) three days without shaking; after which, decant the clear Tin∣cture of the Castor, and put it into the Tincture of Opi∣um in the great Glass, as a∣foresaid. To the Opiate Magma, put the clear de∣canted Tincture of Cloves, &c. which shake well toge∣ther twice a day for three days; then let the Glass stand (as as also the Fifth Glass containing the Tincture of Virginian Snake-root, &c.) 3 days without shaking; after which decant the clear Tin∣cture of Cloves, and put it to the Tincture of Opium in the great Glass, as afore∣said. Lastly, to the Opiate Magma, put the clear decan∣ted Tincture of Virginian

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Snake-root, &c. which shake together twice a day for three days; then let it stand three days without shaking; decant the clear Tincture, and put it to the former; the which keep in a Glass close stopp'd. In these Tin∣ctures dissolve Narcotick Sul∣phur of Vitriol, †††††††A. ℥i. shake them, digest ten days, and keep the whole for Use.

171. The Virtues are equal to the best and most exalted Laud. which you may see lib. 2. cap. 8. sect. 7. of this work. Dose a gut. x. ad xv. xx. or xxx. in a Glass of Sack, Cinnamon Water, or other fit Vehicle.

172. Secondly, with Spi∣rit of Sulphur, or depurated Juice of Gitrons.

Take five Glasses holding a pretty deal more than a Quart a piece; into four of which put a Quart or better of Spirit of Sulphur, or depurated Juice of Ci∣trons, with their other pro∣per Ingredients in the same quantities as in the former; and into the fifth Glass put of the afore-mentioned S. V. with Volatile Salt of Tartar, into which the Saffron and Cochinele are to be put; di∣gest all severally for a month, shaking them twice a day, and perfect the work in all respects by the former dire∣ctions.

The Vertues and Dose are the same with the former, save this is better in hot, dry and Cholerick Constitutions, and for such as have a Heat and Boyling in their Sto∣machs.

Examples in compounding Cordials and Antidotes.
I. Cardiacks which cheer the Heart by Accension, en∣kindling or heating the Blood.

173. ℞ AQuae Coelestis ℥ii. Borrage Water ℥ii. Syrup of Clove∣gilliflowers ℥iss, mix them for a draught.

174. ℞ Aquae mirabilis ℥iss. Angelica water the greater Composition ℥i. Sy∣rup of Citrons ℥iss. mix them.

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175. ℞ Aquae Vitae Mat∣thioli (that is Aquae Coelestis) Aquae Mirabilis, A. ʒiii. Be∣zoartick Water of Langius ʒiv. choice Canary ℥i. Syrup of Quinces ℥iss. mix.

176. ℞ Wormwood wa∣ter the less Composition ʒ ii. Lavender water compound ʒ iii. Confectio Alkermes ʒ iv. simple Bawm water, Syrup of Violets, A. ℥iss. mix them.

177. ℞ Elixir Vitae ma∣jus of Quercetan ʒ i. Spi∣rit of Angelica the greater Composition ʒ ii. Tinctu∣tura aurea ʒ iii. Bugloss water, Syrup of Coral, A. ℥i. mix them,

178. ℞ Cinnamon wa∣ter ℥iss. Syrupus Cardiacus ℥ii. mix them.

179. ℞ Cinnamon wa∣ter, Wormwood Water, A. ℥ss. Tinctura Vitae nostra ʒ vi. Syrup of Quinces ℥i. mix them.

180. ℞ Spirit of Worm∣wood the greater Composi∣tion ℥i. Oyl of Cinnamon gut. iv. choice Canary ℥ii. Syrup of Citron peels ℥i. mix them.

181. ℞ Cinnamon wa∣ter, Angelica Water, the grea∣ter Composition, Confect of Alkermes, A. ℥ss. Bezo∣artick water of Langius ʒ vi. Sage Water ℥ii. mix them.

182. ℞ Cinnamon wa∣ter, Bezoartick water, A. ℥ss. Spirit of Lavender ʒ ii. Tinctura aurea ʒ i. Sage water ℥iii. Syrup of Clove Gilliflowers ℥iss. mix them.

183. Treacle Water ℥ss. Aquae Mariae ℥i. Scordium water compound ʒvi. Parsly water ℥ii. Syrup Bizan∣tine compound ℥ss. mix them.

184. ℞ Tincturae vitae no∣strae, Bawm Water the grea∣ter Composition, A. ℥ss. Cinnamon water ʒ vi. Sage Water, Syrup of Li∣mons. A. ℥ss. mix them.

185 R. Cinnamon wa∣ter of Matthiolus ℥i. Syrup of Bawm, and of Citron peels, A. ℥ss. Spirit of Ro∣ses gut. xii. mix them; 'tis an admirable Cordial.

186. R. Wormwood water, Imperial Water, A. ℥ss. simple distilled Water of Time ℥ ii. Syrup of

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Citron Peels ℥j.ss. mix them.

187. ℞ Bezoartick wa∣ter, Clove water A. ʒij. Tincture of Salt of Tartar ʒj. Oyl of Cinnamon gut. iv. Sage water ℥iij. Syrup of Betony compound ℥ij. mix.

188. Aqua Imperialis Ca∣roli Quinti Imperatoris. ℞ Lillies Convally, red Ro∣ses, A. lbiij. Lavender flow∣ers lbj. Rosemary flowers lbss. Betony M. vj. Rue M. iv. Sage M. iij. Take each in their best Season, and put them into S. V. lbviij. This done, add Cin∣namon bruised lbj. Grains of Paradise ℥v. Cubebs, Nutmegs, A. ℥iv. Cloves, Mace, Caraway Seeds, Am∣ber A. ℥iij. Ambergrise ℥ss. bruise all that are to be bruised, and affuse thereon Rhenish wine lbxxxvj. di∣gest 3 or 4 days, and distill either in a Glass Alembick, or in a Copper Vesica well tinn'd within: The first 24 pints keep by it self, the rest for an ordinary Water. The first 24 Pints being dul∣eified with Sugar, may be drank as need requires, in all Fainting and Swooning Fits, a ʒij. ad ℥ss. it is also good in a Vertigo, Head-ach, Dim∣ness of Sight, loss of Memo∣ry, &c.

189. ℞ Of the aforesaid Impertal Water, Angelica Water, the greater Compo∣sition, A. ℥ss. Syrup of Ci∣tron, and of Clove Gilli∣flowers A. ʒvj. simple Bawm water ℥j. mix.

190. ℞ Aqua Vitae Mat∣thaeoli, Syrup of Citrons, Borage Water, A. ℥ss. simple Angelica water ℥jss. mix them, and give it upon fainting.

II. Cordials or Cardiacks which allay the too great Ef∣fervescency or Accension of the Blood.

191. ℞ DIstilled Rain water lbjss. Syrup of Clove-Gilliflowers ℥jss. Juice of Limons ℥j. Spirit of Sulphur gut. xxj. mix them. Dose ℥ij. or more when you pleare.

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192. ℞ Waters of Wood-Sorrel, of the whole Citron, of Strawberries, A. ℥vj. Syrup of Limons, or of the Juice of Citrons ℥iss. Pearls prepared ʒj. Dose ℥ij. three or four times a day.

193. ℞. Distilled Wa∣ters from Pipins or Pear∣mains, of Rasberries, A. ℥ix. Syrup of Violets ℥jss. Spirit of Vitriol or Sulphur, gut. xviij.mix and make a Julep

194. ℞ Yellow Sanders, Conserve of Citron Peels, of Flowers of water Lillies, of Violets, of Roses, Pearls prepared, Raspins of Ivory, Bone of a Stags Heart, Frag∣ments of Jacynths, of Eme∣ralds, of Saphyrs prepared, red Coral prepared, A. ʒi. Sorrel seeds ʒij. choice Musk ℈i. Juice of Alkermes q. s. mix and make a Conserve. Dose a ʒss. ad ʒi.

195. ℞ candied Eringoes ℥vi. Grass roots ℥iij. Ken∣tish Pipins sliced, No. ij. Shavings of Harts-horn and Ivory, A. ʒij. Leaves of Wood Sorrel M. j. Spring water lbiij. boyl all to lbij. strain out, and add Syrup of Violets and of Clove Gilliflowers, A. ℥j. Sal pru∣nellae ʒij. mix and dissolve. dose ℥iij. or more thrice a day.

196. ℞ Barly Broth lbij. Syrup of Citrons ℥ij. Cry∣stalls of Tartar ℥ss. dissolve and give ℥iij. or iv. 3 or 4 times a day.

197. ℞ A strong Deco∣ction of Borage, Bugoss, and Bawn lbij. Syrup of Vio∣lets, and of Citrons, A. ℥i. Tartar vitriolate ʒj. mix and dissolve. Dose ℥iij.

198. ℞ Conserve of red Roses vitriolated ℥iv. Spring water lbii. dissolve over a gentle heat, and strain. Dose ℥iij. ad libitum.

199. ℞ Conserves of red Roses vitriolated, and of Violets vitriolated, A. ℥iij. water of the whole Limon or Citron lbiij. dissolve and strain; to the straining add Juice of Alkermes ℥iii. mix them. Dose ℥iv. at pleasure.

200. ℞ Conserve of Wood Sorrel, Rob. of Ras∣berries, A. ℥ii. Confect of Hyacinths ℈iv. Pearls pre∣pared ℈ii. Syrup of Juice of Citrons q. s. make a Con∣fect. Dose ʒss. thrice a day.

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III. Cordials or Cardiacks, which open the too strict joint∣ing of the Blood, that thereby in its Fermentation, its Su∣perfluities may be the more easily separated and expelled; and these are for the most part Salines, either Volatile, or Alcalizate, or Acid, or Fixed, or Nitrous.

FIrst, Cardiacks, whose Basis is a Volatile Salt, as Spirits of Harts-horn, Sal Armoniack, Elks Hoofs, Cra∣nii humanii, Amber, Virgi∣nian Snake-root, Contra yer∣va, Mithridate, Treacles of all sorts, Zedoary, Salt of Vipers, of Amber Man's Skull, Ashes of Toads, &c.

201. Spirit of Elks hoof a gut. xv. ad xx. Aquae vi∣tae Matthioli ʒii. Spirit of Sulphur gut. ij. give them in an appropriate Liquor.

202 ℞ Spirit of Man's Skull, gut. xviii. Treacle∣water ʒiiss. mix them, and give the mixture in some specifick Vehicle.

203. ℞ Water of Birth∣wort Leaves lbj. waters of Penny-royal, of Hyssop, A. ℥iv. Aqua mirabilis, aqua Lumbricorum, and Water of Snails, A. ℥j. Syrup of Clove Gilliflowers ℥iss. mix and make a Julep.

204. ℞ Spirit of Harts∣horn ʒi. Tincture of Anti∣mony ℥i. mix them: the Dose a gut. xx. ad xxx.

205. ℞ Spirit of Harts∣gut. 20. Treacle water ʒii. Spirit of Sal Armoniack gut. ii. mix, and give in a pro∣per Vehicle.

206. Spirit of man's Blood ℈i. Aquae Vitae Mat∣thioli ʒiiss. Bawm water sim∣ple ℥iv. mix them.

207. ℞ Spirit of Soot gut. xv. Aqua mirabilis ʒiss. An∣gelica water, the greater composition ʒii. mix and give in a proper Vehicle.

208 ℞ Spirit of Harts∣horn, Spirit of Sal Armoni∣ack, A. gut. vi. Wormwood water the greater compositi∣on ℥ss. mix, and give in a fit Vehicle.

209. ℞ Salt of Vipers ʒi. Sal prunellae ʒii. pulvis ex chelis Canctorum compositus ʒiss. mix and make a Pow∣der. Dose a ʒi. ad ʒiss.

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in a Spoonful of Syrup.

210 ℞ Flowers of Sal Ar∣moniack ℈ss. Bezoar Mineral ʒi. Make a Powder to be given in some Cordial Sy∣rup or proper Liquor. These last ten may he profitably given in all sorts of Fevers in re∣spect of the Blood, as also in Swoonings, and suddain Lan∣guors, in respect of the Ani∣mal Spirits.

Secondly, Cardiacks, whose Basis is an Alchalizate Salt; such are Bezoar Stone, Pearls, Coral, Bone of a Stags Heart, Harts born crude, I∣vory in Powder, Crabs Eyes and Claws, Oyster shell, Ter∣ra sigillata, and other stony & earthy Substances of like Nature.

211. ℞ Prepared Coral, Pearls, A. ʒii. Bezoar Stone, and Bezoar Animal, A. ʒss. white Amber prepared ℈ii. Ambergrise ℈i. mix and make a Powder. Dose ʒss. twice or thrice a day in some proper Syrup or Wa∣ter.

212. ℞ Pulv. ex Chelis Cancrorum Compos. ʒiss. pearl prepared, Man's Skull pre∣pared, Male-peony Roots, A. ℈iv. Flowers of Male∣peony, of Lilly, Convally, A. ʒss. make a Powder to be taken as aforesaid.

213. ℞ Pearl, red Co∣ral, white Amber, Ivory, all prepared, A. ʒiss. Species Diambrae ʒi. white Sugar dissolved in Aqua Rosarum, and boyled to a Consistency ℥vii. make Tablets weigh∣ing half a ʒ to eat one, two or three often in a day.

214. ℞ Conserve of Lil∣ly, Convally ℥ iiii. of Flow∣ers of Sage, ℥ii. Powder of Coral, of Pearl, Crabs Eyes, and Ivory prepared, A. ʒiss. Vitriol of Steel ʒ i. Syrup of Coral q. s. make an Ele∣ctuary. Dose a ʒ i. ad ii. twice a day, drinking af∣ter it some Cordial Julep, as the following.

215. ℞ Waters of Flow∣ers of Lilly Convally, of Pe∣ony, or of the Tile Tree, of the whole Citron A. ℥ vi. Water of Rinds of O∣ranges distilled with Wine ℥ ii. Syrup of Violets ℥iss, mix them.

216. ℞ Gascoin's Pow∣der or of Crabs Claws com∣pound

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℥j: Bezoar Animale ʒij: Salt of Vipers ʒj: mix and make a Pouder, dose a ℈ ss ad ℈j, or more in Sy∣rup.

217. ℞ ••••iental Bezoar, Bezoar animal, Bezoar mi∣neral, A. ʒ ij: mix them in a fine pouder. Dose a gr. vj ad ℈j, or more.

218. ℞ Pouder of Crabs Eys and Crabs Claws, A. ʒj: Pearl, Coral, and Amber prepared, A. ℈jv: Bezoar Oriental and Animal, A. ʒss: fine Bole, Diaphoretick Gold A. ℈ij: Bezoar mineral ʒj; mix in a fine pouder: dose a ℈j ad ʒj:

219. ℞ Ivory, Coral, Am∣ber, all prepared, A. ʒ ij: Species Diambrae, ʒj: Salt of Steel ʒ ij: Sugar ℥ viij. Ambergrise in fine pouder ℈ ss: make Tablets weighing ʒ ss: Dose ʒ iij, or ℥ ss: twice a day.

220. ℞ Coral prepared, flowers of Sal Armoniack, Amber prepared, A. ʒ ii: Sal prunellae, pouder of red Poppy flowers, A. ℈jss: Dose ℈i twice a day in a proper Vehicle.

221. ℞ Sal Prunellae ʒij: Salt of Amber ʒ i: Pearl, Coral prepared A ʒ ss: Salt of Harts horn ℈ j: mix in a fine pouder: Dose gr. xv. ad ʒ ss: in a proper Vehicle, The Eleven aforesaid are most proper in Plourisies, Trem∣blings and Palpitations of the Heart, for that they destroy the Powers of the acid Salts: and so hinder the Coagulati∣ons and Extravasations of the Blood.

Thirdly. Cardiacks, whose Basis is an Acid Salt, or Fluid Salt, such are all ace∣tous Medicines, as, Vinegar, Treacle Vinegar, Bezoar∣tick Vinegar, Spirit of Vitri∣ol, Sulphur and Salt: juy∣ces of Sorrel, of Wood-Sor∣rel, of Pomgranates, of O∣ranges, of Limons, of Ci∣trons, with many others of the same kind.

222. ℞ Prophylactick wa∣ter of Sylvius ℥ ij: Sy∣rup of the Juyce of Ci∣trons ℥ ss: Angelica water à ℥ i ss: mix them: Dose à ʒ ij ad ʒ iv.

223. ℞ Some Cordial water ℥ jv: Syrup of the Juyce of Citrons ℥ ss: Trea∣cle water ʒ ii: Pearls prepa∣red

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℈ss. spirit of Vitriol agut. iij ad vj: make a drink to be taken twice or thrice a day.

224. ℞ Spring water lb iv: Juyce of two large Limons, Syrup of Clove-gil∣ly-flowers ℥ iij; Hypocra ss ℥ ij, mix: Dose ℥ iv, or more, 3 or 4 times a day.

225. ℞ ashes of Harts∣horn ʒ iij: spirit of Vitriol ʒ i: mix them in a glass-Mortar and dry them: Dose à ℈j ad ʒ ss: in 2 or 3 spoon∣fuls of a Cordial Julep.

226. ℞ Antimony Dia∣phoretick or Bezoar Mineral ℥ ss: Spirit of Salt ℈ iv: mix and dry, as asoresaid: and give à ℈ j ad ʒ ss in a glass of white wine and Su∣gar.

227. ℞ Fresh Sraw-ber∣ries lb viij: whitewine lbviij; Oranges, peel and all, slic'd: No xii: let them serment in a close Vessel, with filings of Steel lb ss, for 24 hours: then distil in a Copper A∣lembick tin'd within: Dose ab ℥ j ad ij or iij: Of like na∣ture with these things is the Divine Drink of the Palm Tree. These 6 or 7 last things with an innumerable others prepared from acid or sluid Salts, are great Alex∣iterians, curing all malignant Feavers, yea and are good in the Plague it self; for that they unlock the joyntings or Combinations of the sixed Salt with the adust Sulphut in the blood in Feavers; whereby the Coagulations, and Extravasations of the Blood, which commonly hap∣pen in all malignant Fea∣vers, are often prevented or suddenly cured.

Fourthly, Cardiacks, whose Basis is a fixed or lixivial Salt, made by Incineration, Elixiviation, and Evaporati∣on, from Vegetables, Ani∣mals, and some kinds of Mi∣netals.

228. ℞ Carduus Water or Mynsicht's Aqua febrisu∣ga ℥ iij: Salt of Worm∣wood ℈ j: Oyl of Sul∣phur ℈ ss: mix them to be taken 2 or 3 hours before the Paroxism of a Feaver.

229. ℞ Waters distilled from the whole Citron slic'd, from Wood Sorrel, A. lb ss: Sugar ℥ ss: Juyce of Limons ʒ ij: Salt of Tartar ʒ i ss: Salt of Wormwood ʒ ss: mix

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and make a Julep, to be given in any irregular Fea∣ver, having sharp sits, day by day without shaking.

230. ℞ Simple Bawm wa∣ter and Angelica Water, A. ℥ ii: Salt of Centory the less ʒ ss: Syrup of Clove-gilli∣slowers ℥i: mix them.

231. ℞ of the Alexandri∣an or Royal Julep ℥vj: Salts of Centory the less, of Worm∣wood, of Garduus, A. ℈ ss: Syrup of Citron Juyce ℥ ss: mix them.

232. ℞ Prophylactick wa∣ter of Sylvius ℥ ss: Salt of Tartar gr.xv. water of Cen∣tory the less ℥ iij: mix them for a draught.

233. ℞ Carduus water ℥ jv: Salts of Centory the less, & of Wormwood, A. ℈ss: Oyl of Vitriol, gut viij: Sy∣rup of Centory ℥ j: mix them.

234. ℞ Ftherfewwater ℥ iij: Salt of Broom and of Germander, A. ℈ ss: Salt of Tartar Vitriolate gr. xv: Syrup of Violets ℥j: mix them.

235. ℞ Spring water ℥iij: Salt of Wormwood or of Tartar ℈j: Syrup of the Juyce of Limons ℥j: mix them for a Dose. These 8 last things are Alexipharma∣cons, of singular use in seve∣ral kinds of Feavers whereby the Enormities of acid Salts reigning in the Viscera and the Blood, are corrected: and as there are divers sorts of Salts generated in the human Body, which pass every where from one state to another: so ought there to be given for every Intention, Salines not of one but of a diverse kind.

Fiftly, Cardiacks, whose Basis is a Nitrous Salt, such as pure Niter it self, Sal prunellae, as Antimonial Niter, &c. whose Particles being inspired with Air, up∣holds and maintains the life of Animals: The Lord Ba∣con truly observes, That the Particles of Niter being car∣carryed into the Ventricle, and also inspired together with the Air (where, joy∣ned with certain sulphurous Particles, they make a flame, which) conduces much to the conserving and prolonging of our Life.

236. ℞ Spring water lb ij: Sal Prunellae ʒ j ss: Sy∣rup

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of Clove Gilliflowers: ℥ vj: mix them: dose ℥ iij or ℥jv: 3 or 4 times a day.

237. ℞ Fennel Water lbij: flowers of Niter ʒ ij: Vola∣rile Salt of Amber à ℈ j ad ʒ ss: Syrup of Violets ℥ iv or vj: mix them, and give it as the former.

238. ℞ of the Alexandri∣an Julep, lb j: Antimonial Sal prunel ae ℈ iiss: volatile Salt of Harts-horn, gr. x Sy∣rup of Limons ℥ i: mix them for ij Doses.

239. ℞ Confection of Alkermes ℥i: Lapis Pru∣nellae in sine pouder ℈ij: Sal Cranij humani ℈j: mix for two Doses to be taken morning and night.

240. ℞ Electuarium Sto∣machicum Mynsichti ℥ ss: Mithridate ʒ ij: Elect. de Ovo ʒj: Sal Prunellae ʒij: mix for iv doses.

241. ℞ Venice Treacle ℥j; flowers of Niter ʒiij, Salt of Ox horns: ʒj: mix them well: Dose à ʒi, ad ʒ i ss: or ʒ ij.

242. ℞ Elect. Diatessa∣ron ℥j: Sal Prunellae ʒij; Sal Absinthij, Salt of Amber, A. ℈j: mix for 4 or 6 Do∣ses.

243. ℞ Sal prunellae ℈j: volatile Salt of Harts-horn gr. iij: Volatile salt of Am∣ber gr. ij: mix them in a pou∣der, and give it in a spoonful of Syrup of Bawm.

244. ℞ Salt of Worm∣wood, Oriental Bezoar, Sas∣fron, A. gr. x. Bezoar mine∣ral gr. viij: Sal Prunellae à ℈ i ad ʒ ss; mix, and give it in Syrupus Cardiacus; see it in Our Pharm. Lond. lib. 4. cap. 16. sect. 16. the Author of it was Ʋffonbachius.

245. ℞ Bezoar Mineral gr. x. Pulvis Cardialis Fer∣nelii magis compositus, Lapis Prunellae, A. gr. xxvj. mix, give it as the former.

IV. Alexiterian Cardiacks, or Antidotes preservatory.

246. ℞ Aqua Cardiaca ℥ ij: Powers of Angelica, gut. xx. Powers of Worm∣wood, gut. x. Syrup of Ci∣tron-peels ℥ ss: mix, and take it twice or thrice a day.

247. ℞ Bezoartick water of Langius, Syrup of Worm∣wood, compound, A. ℥ ss:

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choice Canary ℥ iij: mix them, and take it in the mor∣ning fasting, and at night go∣ing to bed.

248. ℞ Cinnamon water of Matthiolus, Tinctura au∣rea, A. ʒ ij: Syrup of Bawm compound ℥ ss: Electuari∣um de ovo ʒj: mix and take it thrice a day.

249. ℞ Prophylactick water of Silvius, aqua Epi∣demica, A. ʒ ij: Syrup of Peony compound ℥ ss: choice Canary ℥ iv: mix, and give it 2 or 3 times a day.

250. ℞ Aqua magna of Phioravant, and his Aqua ad Pestem, ana ℥ij: Syrup of Clove-Gilliflowers ℥jss: Ca∣nary ℥ ij: mix, and take it morning and evening. Dose ℥ j.

251. ℞ Spiritus Cardia∣cus ℥ iij: simple Angelica water ℥ ji, Syrupus Regius ℥ i ss:mix, and let it be ta∣ken 3 or 4 times a day.

252. ℞ Choice Canary, ℥ iij: Elixir Proprietatis, gut. xx. Syrupus de staechade ℥ j ss: mix them well, and let it be taken 2 or 3 times a day.

253. ℞ Prophylactick wa∣ter of Sylvius, Treacle water A. ʒ ij: Syrup of dry'd Ro∣ses ℥ ss; Canary ℥ j ss: mix to be taken twice or thrice a day or oftner.

254. ℞ Tinctura Cardia∣ca, Tinctura Corticum, Trea∣cle Water, A. ℥ i: Canary ℥ vi: Syrup of Violets ℥ iij: mix, and let it be taken three times a day: dose ℥ j or ℥ iss.

255. Aqua Angelicae the greater Composition, water of Butterbur compound, A∣qua Epidemica, Aqua Bezo∣artica Langij, Aqua Impe∣rialis, Aq. Mirabilis, Aqu. Caelest is, Scordium-water compound, Prophylactick water of Sylvius, A. ℥j: choice Canary ℥xiij ss: Sy∣rups of Citron peels, of Clove gilliflowers, of Staechas, of dryed Roses, and the Juyce of Violets, A. ℥j, ʒvj: mix them well together. Dose ab ℥ j ad ℥ij; or more se∣veral times of the day.

256. ℞ of the Virginian Snake-root, Contrayerva both bruised, A. ℥ ss: Ze∣doary bruised, Saffron, A. ʒii: Cochenele bruised, Camphir, A. ʒj. S. V. re∣ctified, a quart: put all in∣to

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the Spirit, except the Cam∣phir: digest 12 daies in a cool place, shaking it 2 or 3 times every day: then letting it stand 3 dayes to settle, decant off the clear into a clear Gla ss, into which put the Camphir (first dis∣solv'd in 2 spoonfuls of recti∣fied S.V.) and keep it close stop'd for use. Dose gut. 40 or 50 in a little Canary, or any fit Vehicle, several times a day.

257. ℞ Mountain Cala∣minth, Carduus, Scordium, Goats-Rue, Lavender, Bawm, Rosemary, A. M. j: Roots of Avens, of white Dittany, of Masterwort, yellow of O∣range Peels; A. ℥j: Myrrh, Cinnamon, Cloves, A. ℥ss: Sassron ʒj: Aqua Vitae lbviij: digest 10 or 12 days, thaking it every day, then letting it settle: Decant the clear for use: Dose ab ℥ ss: ad ℥ j.

258. ℞ Radix serpenta∣ria ℥ jv: boil in Spring wa∣ter lb jv: to the Consump∣tion of the half: strain, and add Honey ℥ ij ss: Venice Treacle ℥ j ss: Tinctura au∣rea ℥ vj: mix, dissolve hot, strain again and keep it for use. Dose 2 or 3 spoon∣fuls 3 or 4 times a day.

259. ℞ flowers of Sulphur ℥iiij; melt them in a Cruci∣ble, to which add, by spoon∣fuls one after another, sal Absinthii ℥ jv: mix till the Ma ss grows red: then put to it pouder of Aloes, Mirrh and Olibanum, A ʒj: saffron ʒss work them together for a∣bove a quarter of an hour, till they be incorporated: the Mass being cooled and put on a Marble or Glass plate, to melt into a fair Oyl like a Ruby to see to. Dose à gut. 10 ad 20 in ℥ j ss or ℥ ij of Bezoartick water. Willis.

260. ℞ of the former pouder q.s. put upon it Tin∣ctura vitae, or Tincture of Virginian Snake-root and Contrayerva in S.V. so much as may over-top it 3 Inches, and extract the Tincture: Dose à gut. 20 ad 30. in a fit Vehicle.

261. ℞ of the former pouder ℥ ss: generous Wine lb ij: dissolve it in a close Vessel and warm: Dose one Spoonful twice or thrice a day.

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262. ℞ Oriental Bezoar, Viper pouder, A. ℥ j: Contra∣yerva, Virginian snakeroot, both in fine pouder, A. ℥ ss: species Liberantis ʒij, Cam∣phir ʒ ss; mix them. Dose à gr. xvj ad ʒ ss: in any proper Syrup or Vehicle.

263. ℞ Viper pouder, In∣dian Cachunde. A. ℥ ss: Be∣zoar minerale, Bezoar stone A. ʒ ij: Compound pouder of Crabs Claws, Camphir, A. ℈j: mix. Dose à gr. xv. ad ʒ ss.

264. ℞ Virginian snake∣root, Contrayerva, both in sine pouder, Zedoary in fine pouder; Cloves, Nutmegs, in fine pouder, species Libe∣rantis, A. ʒij: Camphir ℈ij ss; Sugar dissolved in Bezoartick Vinegar and boi∣led to a Consistency ℥ viij; make Tablets according to Art weighing ʒ ss: or some∣thing less: to be eaten 1 or 2 often in a day.

265. ℞ Conserve of leaves of Rue ℥ iv: Mithridate, Confectio Liberantis, A. ℥ j: Confectio de Hiacintho ʒ ij: Salt of Wormwood ʒ ij ss: pouder of red Cloth (or in stead thereof Cochenele) ℥ ss Bezoartick Vinegar, q. s. make an Electuary; Dose the quantity of a Chesnut thrice a day.

266. ℞ Venice Treacle ℥ ij: Electuarium de Ovo ℥ j: Viper pouder ℥ ss, Camphir ʒss: mix, and make an Electuary. Dose ʒ ss: 2 or 3 times a day, drinking after it a Glass of Canary.

267. ℞ Venice Treacle ℥j ss: Compound pouder of Crabs Claws ʒ ij: Bezoar stone ʒj: Camphir ℈ j; mix and with a little Bezoartick water, make an Electuary Dose ʒ ss.

268. ℞ Conserves of Marsh Wormwood, of Scor∣dium, of Rosemary flow∣ers, of Sage flowers, ana ℥ ss: Venice Treacle ℥ ij: Bezoar Mineral, Viper pou∣der, A. ʒ vj: mix, and with a little of the Bezoartick wa∣ter of Langius make an Ele∣ctuary. Dose ℈ i 3 times a day.

269. ℞ Laudanum Para∣celsi gr. ii, iij, or jv: Orien∣tal Bezoar as much: mix them well together, and take it ev'ry night, drinking a glass of Sack after it.

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270. ℞ Laudanum opia∣tum gr. ij or iij: Oriental Bezoar gr. vj: Venice Trea∣cle ℈i: mix them, to be ta∣ken every night going to bed.

V. Alexiterian Cardiacks, Or Antidotes Curatory.

After the Infection or Contagion has seized, all the former things may be given, but in a greater Dose, and oftner; as also both ace tous things, and the fixd Salts of Herbs, for that the Crasis of the Blood being vitiated and corrupted, they dissolve all its Coagulations, and Hetrogeneous particles what soever, which being transpi∣red, its liquor at length reco∣vers and retains its prestin state and condition.

271. ℞ Bezoartick water of Langius ℥ ss: Prophyla∣ctick water of Sylvius ʒ iij: Cinnamon water ʒ j: Cam∣phir gr. v. mix for a Dose.

272. ℞ S V. rectified ℥j: the red Hungarian powder ʒ ss: mix and keep it close stopt for 8 or 10 hours: then add thereto Saffron, Coche∣nele, Viper-pouder, A. ℈ ss: Canary 〈◊〉〈◊〉 jv: mix, and shake all well together, and give it at once, to sweat upon.

273. ℞ Oriental Bezoar, Mineral Bezoar, Viper-pou∣der, Mosaick Gold, A. gr. x. Camphir gr. v. Laudanum opiatum gr. i. or ij: mix, and add thereto Spirit of Ange∣lica the greater Compositi∣on ʒiv: Tinctura Aurea, Treacle Water, A. ʒ ij: Choice Canary ℥ iij: mix for one Dose; & let the sick sweat well upon it.

274. ℞ Treacle-water ℥j ss: Venice Treacle ʒ ij Electuar. de Ovo ℥ ss: mix.

275. ℞ Aqua Cardiaca ℥ jv: Spiritus Cardiacusss Diascordium of Silvius ℈j: mix, and give it the sick warm: you may sweeten with Syrup of Clovegilliflowers, or of Citrons.

276. ℞ Aquae Cardiaca, prophylactick water of Svl∣vius, A. ℥ij: Confectio Al∣kermes Chymica ℈j: vipei∣pouder ℈ ss; Camphir gr. iv: mix for one dose.

277. ℞ Bezoartick water ℥ij ss: Bezoartick Vinegar ℥ ss: Venice Treacle ʒ j:

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mix them well by shaking in a glass, for a Draught to pro∣voke sweat.

278. ℞ Whitewine, Ca∣nary, A. lb j: Virginian Snakeroot, Contrayerva, Carduus Leaves, A. ℥j: boil and make a strong Decocti∣on; strain and dissolve there∣in Venice Treacle ℥ ss: to which add of the King of Po∣land's Vinegar ʒj: Saflron ℈ j in pouder: Sweeten with Syrup of juyce of Citrons, & of Clovegilliflowers, A. q. s. and make two Draughts to be taken in 12 hours space to sweat upon.

279. ℞ Waters of Ange∣lica, of Carduus, of Dragons, A. ℥jv: of Scordium Com∣pound ℥ ij: of Bezoartick water, Treacle water, A. ℥ j pouder of Pearls ʒ i: Syrup of Clove Gillislowers (or of juyce of Citrons) ℥ij: Spirit of Vitriol, gut. xij: mix and make a jusep: Dose ℥iij, often in a day: sometimes alone, sometime with other Medicines. Willis.

280. ℞ Aqua Cardiaca ℥xij: Treacle water, Aqua Epidemica, Bezoartick water A. ℥ iss: Prophylactick wa∣ter of Sylvius, Tinctura au∣rea A. ℥ ij: Syrup of Li∣mons ℥ iij: Oyl of Sulphur gut. xvj: mix them. Dose 3 or 4 spoonfuls.

281. ℞ Damask Rose-Water, Angelica water, ana, ℥ vj: Spirit of Angelica the greater Composition, Aqua Epidemica, Treacle water, Syrup of Limons, A. ℥ iiss: dissolve therein Venice Trea∣cle, Orvietan the greater Composition, Elect. de Ovo, A. ℥ i: Dose ℥ ij or more at a time, 2 or 3 times a day.

282. ℞ Bezoar Mineral ʒ ss: Venice Treacle ʒ j: Camphir gr. vj: Bezoartick Vinegar q. s. make a Bolus, to be swallowed alone, or ta∣ken dissolv'd in some proper Vehicle: drinking after it a draught of cordial Julep.

283. ℞ Oriental Bezoar ℈j: Electuarium de Ovo ʒ ss Extract of Contrayerva, pou∣der of Saffron, A. ℈ ss: Cam∣phir gr. jv; make a Bolus, which take as the former.

284. ℞ Viper pouder ʒss, Venice Treacle ʒ i: Saffron ℈ ss: Camphir gr. v. Tar∣tar vitriolate, gr. vii: mix and make a Bolus to be ta∣ken

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as the former.

185. ℞ Venice Treacle ʒ i; Viper pouder, Orien∣tal Bezoar, Bezoar mineral, Saffron, Cochenele, in fine pouder, A. ℈ ss: Camphir gr. jv: Laudanum Opiatum gr. j or ij: Bezoartick Vine∣gar, q. s. make a Bolus, to be taken, as abovesaid:

286. ℞ Pouder of Toads, (made by a Close Calcina∣tion) prepared, pouder of Crabs-Claws compound, A. ʒ ss: make a pouder, and give it as the former. Willis.

287. ℞ Venice Treacle, ʒj: Salt of Vipers, gr. xij: mix for a Dose.

288. ℞ Gascoins pouder, pouder of Contrayerva, of Virginian Snake-root, A. ℈j or gr. xxv. mix them, and give it in a spoonful of Trea∣cle water, drinking after it a draught of some cordial Ju∣lep.

289. ℞ Compound Pou∣der of Crabs Claws, Viper∣pouder, A. ℈ j: mix, and give it in a little Treacle-wa∣ter.

290. ℞ Bezoar oriental gr. vi or viii: Laudanum Paracelsi gr. iii or iv: mix and give it, and let the sick take after it a little Aqua Epidemica, or a draught of choice Canary, and so sweat upon it.

There are hundreds of other Ingredients, which. you may find in our Books, and of which you may make a thousand other Compositi∣ons of equal force and vir∣tue, in imitation of these Examples: of which you may see a plentiful speci∣men in our Synopsis Me∣dicinae, lib. 3. cap. 33. sect. 21. The very place where we treat of the Cure of the Plague or Pestilence, to which we refer you.

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