AIDS Medicines: In Development, Drugs and Vaccines

AIDS Medicines In Development
Approved Medicines
DRUG NAME COMPANY INDICATION U.S. DEVELOPMENT STATUS
Bactrim"t Hoffmann-La Roche PCP treatment approved
Trimethoprim and (Nutley, NJ)
Sulfamethoxazole
Cytovene~ Syntex CMV retinitis approved
Ganciclovir (IV) (Palo Alto, CA)
DARAPRIM~ t Burroughs Wellcome toxoplasmosis treatment approved
Pyrimethamine (Rsch. Triangle Park, NC)
Diflucan Pfizer cryptococcal meningitis, candidiasis approved
Fluconazole (New York, NY)
Intron A~t Schering-Plough Kaposi's sarcoma approved
Interferon-alpha 2b (Madison, NJ)
NebuPent* LyphoMed PCP prophylaxis approved
Aerosol Pentamidine (Rosemont, IL) (Orphan Drug)
Isethionate
Pentam~ 300 LyphoMed PCP treatment approved
IM & IV Pentamidine (Rosemont, IL)
Isethionate
Retrovir* Burroughs Wellcome advanced ARC, AIDS approved
Zidovudine; AZT (Rsch. Triangle Park, NC)
Roferon~-At Hoffmann-La Roche Kaposi's sarcoma approved
Interferon alfa-2a (Nutley, NJ)
Septra~t Burroughs Wellcome PCP treatment approved
Trimethoprim and (Rsch. Triangle Park, NC)
Sulfamethoxazole
Antivirals
DRUG NAME COMPANY INDICATION U.S. DEVELOPMENT STATUS
AzdU Triton Biosciences HIV positive symptomatic, ARC, Phase I
Azidouridine (Almeda, CA) AIDS
Butyl DNJ G. D. Searle ARC, AIDS Phase I
Deoxynojirmycin (Chicago, IL)
CD4-IgG Genentech ARC, AIDS Phase I
CD4 Immuno- (S. San Francisco, CA)
adhesin
Compound Q Genelabs, Inc. HIV infection, ARC, AIDS Phase I
GLQ223 (Redwood, CA)
Cytovene~ Syntex CMV retinitis Phase I/II
Ganciclovir (oral) (Palo Alto, CA)
Cytovene~ Syntex CMV retinitis Phase III
(Ganciclovir-IV) (Palo Alto, CA)
with Betaseron~
(Recombinant
Human Interferon
Beta)
d4T Bristol-Myers Squibb ARC, AIDS Phase I/II
Didehydrodideoxy- (New York, NY)
thymidine
t-Denotes medicines that have been approved by the FDA for other conditions.
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Copyright ~ 1990 by the Pharmaceutical Manufacturers Association. Permission to reprint is awarded if proper credit is given.