New Medicines: In Development for Children

Infectious Diseases (Viral)

DRUG NAME

COMPANY

INDICATION

U.S. DEVELOPMENT STATUS

Diphtheria and Connaught Laboratories viral poliomyelitis Phase I
Tetanus Toxoids (Swiftwater, PA) (ages 2-18 months)
and Pertussis Pasteur Merieux
Vaccine Adsorbed (Lyon, France)
and Poliovirus
Vaccine, Inactivated
Measles, Mumps Connaught Laboratories measles, mumps, rubella Phase II
and Rubella Virus (Swiftwater, PA) (ages 2-18 months)
Vaccine (Live) Pasteur Merieux
(Lyon, France)
Poliovirus Vaccine, Connaught Laboratories poliomyelitis application submitted
Inactivated (Swiftwater, PA) (ages 2-6 months)
Pasteur Merieux
(Lyon, France)
Respiratory Lederle respiratory syncytial virus Phase I/II
Syncytial Virus (Wayne, NJ)
Vaccine
Rhesus Rotavirus Wyeth-Ayerst viral rotavirus infections, severe Phase II
Vaccine (Philadelphia, PA) diarrhea
Sabin IPV Lederle polio type I, II, III Phase III
Inactivated Sabin (Wayne, NJ) (ages 2 months-5 years)
Polio Vaccine
SQ 32,756 Bristol-Myers Squibb infections caused by varicella-zoster Phase II
(BVaraU) (New York, NY) (ages over 13 years)
Varivax~ Merck chicken pox application submitted
Varicella Vaccine (Rahway, NJ)
Zovirax~ Burroughs Wellcome chicken pox Phase III completed
Acyclovir (Rsch. Triangle Park, NC) (ages 0-18 years)
Metabolic Disorders
DRUG NAME COMPANY INDICATION U.S. DEVELOPMENT STATUS
Cysteamine Warner-Lambert nephropathic cystinosis Phase III completed
(Morris Plains, NJ) (Orphan Drug)
Phosphocysteamine Medea Research cystinosis Phase III
(Port Jefferson, NY) (ages 0-20 years)
(Orphan Drug)
Obsessive-Compulsive Disorder
DRUG NAME COMPANY INDICATION U.S. DEVELOPMENT STATUS
Fluvoxamine Reid-Rowell obsessive-compulsive disorder Phase III
Maleate (Marietta, GA) (ages 8-17 years)
Sertraline Pfizer obsessive-compulsive disorder Phase III
(New York, NY)
Respiratory Distress Syndrome
DRUG NAME COMPANY INDICATION U.S. DEVELOPMENT STATUS
InfaSurf~ Ony respiratory distress syndrome (RDS) Phase III
Calf Lung (Buffalo, NY) (premature infants from
Surfactant Extract 24-32 weeks gestation)

Survanta
Intratracheal
Suspension
Beractant

Abbott
(Abbott Park, IL)

respiratory distress syndrome
(hyaline membrane disease)

application submitted
(newborns)
(Orphan Drug)