Orphan Drugs: In Development
DISEASE DRUG NAME Angioedema C 1-inhibitor (human) (continued) vapor heated SPONSOR Immuno Clinical Research (New York, NY) FDA OFFICIAL DESIGNATION treatment of acute attacks of angioedema DEVELOPMENT STATUS Phase III Anorexia Marinol Unimed for the stimulation of appetite and Phase III dronabinol (Somerville, NJ) prevention of weight loss in patients with a confirmed diagnosis of AIDS Megace~ Bristol-Myers Squibb treatment of anorexia, cachexia, or Phase III megestrol acetate (New York, NY) significant weight loss (> 10% of baseline body weight) and confirmed diagnosis of AIDS OxandrinTM Gynex Pharmaceuticals adjunctive therapy for AIDS patients Phase II oxandrolone (Vernon Hills, IL) suffering from HIV wasting syndrome Saizen~ Serono Laboratories treatment of AIDS-associated Phase II somatropin for (Norwell, MA) catabolism/weight loss injection Bacteremia HA-l1ATM Centocor treatment of patients with gram- application submitted nebacumab (Malvern, PA) negative bacteremia which has progressed to endotoxin shock Blepharospasm DysportTM Porton Products Ltd. treatment of essential blepharospasm Phase II/III clostridium botulinum (Maidenhead, England) toxin type A Botulism, Infant botulism immune California Department treatment of infant botulism Phase II/III globulin (human) of Health Services (Berkeley, CA) Burns epidermal growth Ethicon promotion of cutaneous wound Phase II factor (human) (Somerville, NJ) healing in extreme burn treatment protocols Leucomax~ Schering-Plough treatment of severe thermal injuries Phase III granulocyte/ (Madison, NJ) in patients with greater than 40% macrophage-colony full or partial thickness burns stimulating factor RheothRx~ Burroughs Wellcome treatment of severe burns requiring Phase I poloxamer 188 (Rsch. Triangle Park, NC) hospitalization Cachexia Megace~ Bristol-Myers Squibb (See Anorexia) megestrol acetate (New York, NY) Cancer, Adrenal gossypol Marcus Reidenberg, M.D. treatment of cancer of the adrenal Phase II (New York, NY) cortex Cancer, Bladder INTRON~ A Schering-Plough treatment of carcinoma in situ of Phase III interferon alfa-2b (Madison, NJ) the urinary bladder (recombinant) Photofrin~ QLT Phototherapeutics photodynamic therapy in patients Phase III profimer sodium (Pearl River, NY) with transitional cell carcinoma in situ of urinary bladder Cancer, Bone Ifex~ Bristol-Myers Squibb treatment of bone sarcomas Phase II ifosfamide (New York, NY) Isovorin Lederle for use in conjunction with high- application submitted l-leucovorin (Wayne, NJ) dose methotrexate in the treatment of osteosarcoma Cancer, Brain adenosine Medco Research treatment of brain tumors in Phase I (Los Angeles, CA) conjunction with BCNU Cancer, Breast toremifene Adria hormonal therapy of metastatic Phase III (Columbus, OH) carcinoma of the breast Cancer, Cervical Mitolactol~ Amswiss Scientific treatment of recurrent invasive Phase III dibromodulcitol (New York, NY) metastatic squamous carcinoma of the cervix Cancer, Colorectal 5-fluorouracil Hoffmann-La Roche for use in combination with Phase III (5-FU) (Nutley, NJ) Roferon~-A for the treatment of advanced colorectal carcinoma Immther Immuno Therapeutics treatment of pulmonary and hepatic Phase II disaccharide tripeptide (Moorhead, MN) metastases in patients with glycerol dipalmitoyl colorectal adenocarcinoma
About this Item
- Title
- Orphan Drugs: In Development
- Author
- Pharmaceutical Research and Manufacturers of America
- Canvas
- Page 4
- Publication
- Pharmaceutical Manufacturers Association.
- 1992
- Subject terms
- reports
- Series/Folder Title
- Marketplace > Press releases, reports, and newsletters
- Item type:
- reports
Technical Details
- Collection
- Jon Cohen AIDS Research Collection
- Link to this Item
-
https://name.umdl.umich.edu/5571095.0504.010
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https://quod.lib.umich.edu/c/cohenaids/5571095.0504.010/4
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- Manifest
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https://quod.lib.umich.edu/cgi/t/text/api/manifest/cohenaids:5571095.0504.010
Cite this Item
- Full citation
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"Orphan Drugs: In Development." In the digital collection Jon Cohen AIDS Research Collection. https://name.umdl.umich.edu/5571095.0504.010. University of Michigan Library Digital Collections. Accessed June 10, 2025.