AIDS Research at the NIH: A Critical Review

SUMMARY OF EXPENDITURES: FY 1991
NATIONAL INSTITUTES OF HEALTH
AIDS BY FUNCTIONAL CATEGORY
FY 1991 Estimated Obligations
(Dollars in thousands)
5 NIH
category Amount total
I. BASIC SCIENCE RESEARCHs
A. Biomedical Research:
1. HIV + HIV genome 78,938 9.8%
2. Immunology 70,821 8.8%
3. Blood/blood products 9,542 1.2%
4. Diagnostic methods/reagents development 15,879 2.0%
5. Animal models + related studies 32,016 4.0%
SUBTOTAL, Biomedical research 207,196 25.8%
B. Neuroscience + Neuropsychiatric Research 22,947 2.9%
C. Behavioral Research:
1. Mechanisms of behavior + behavior change 1,780 0.2%
2. Prevention of high-risk behaviors 884 0.1%
SUBTOTAL, Behavioral Research 2,664 0.3%
D. Therapeutic Agents:
1. Development 144,084 17.9%
2. Clinical Trials 196,149 24.4%
SUBTOTAL, Therapeutic Agents 340,233 42.3%
E. Vaccines:
1. Development 56,629 7.0%
2. Clinical Trials 19,247 2.4%
SUBTOTAL, Vaccines 75,876 9.4%
F. Research Enhancement:
1. Training 11,418 1.4%
2. Construction (Extramural) 201 0.03%
SUBTOTAL, Research Enhancement 11,619 1.43%
TOTAL, BASIC SCIENCE RESEARCH 660,535 82.1%
II. RISK ASSESSMENT + PREVHETIONs
A. Surveillance:
1. Diseases associated with HIV 3,845 0.5%
B. Population-Based Research: Natural History,
Transmission, Risk Factors:
1. Transmission:
a. Sexual 31,364 3.9%
b. Intravenous drug users 4,064 0.5%
c. Hemophilia populations 4,756 0.6%
d. Blood recipient/donor studies 8,442 1.1%
e. Perinatal infection 31,396 3.9%
g. Occupationally related 101 0.01%
h. Other/miscellaneous 4,216 0.5%
SUBTOTAL, Transmission 84,339 10.5%
2. Natural history + cofactors 36,234 4.5%
SUBTOTAL, Population-based research 120,573 15.0%