Statement of John F. Brundage, M.D.
STATEMENT OF John F. Brundage, M.D. 1310-1500 8 December 1992 COL Dangerfield began our meeting with a review of the informal 15-6 investigation process and reviewed the tasks for which he is responsible to determine the facts. He then reviewed the allegations that had prompted the investigation. I was asked to describe the events that I was involved with prior to the meeting in Amsterdam. I recalled that, several days before the weekend I was to leave for Amsterdam, I returned to my office to find LTC Redfield sitting there. He said ne had gotten the data that would be the basis for his presentation in Amsterdam and explained his interest in presenting a statistical analysis. I told him the data set was small, and it was not gathered in a way that permitted rigorous statistical analysis. I then went through an approximately 30 minute discussion on statistical methods to compare two groups of data. I suggested that a comparison of mean values would probably not be appropriate and the p value from such a test would not be valid. Unlike a t test, non-parametric tests could be used when data were not from a normal distribution and his data did not appear to be so distributed. I told him rank tests were commonly used for such data. LTC Redfield asked how to do a rank test. I walked him through a simple explanation, and I xeroxed a textbook section that gave step-by-step procedures for rank tests and gave it to him. He then organized his da... did the rank test. I then explained the Chi square and Fischer's exact tests; we did some samples using his data arra2gd in 2 x 2 tables until I thought he understood what I had said. I did not get the impression that this was the end of his analys t. In essence I gave LTC Redfield a short and very basic refresher course in statistical tests. I told him I thought it would be a mistake to emphasize statistical comparisons or p values. However, I thought it likely that someone would ask him. I suggested that he should simply respond that he had done a rank test and give the result. Once again, I cautioned against emphasizing statistical comparisons or p values. It was my impression, when he was working the data in my office, that his sole concern was with the data - he did not seem to be selecting patients to present nor did he seem to be overly concerned with how the answers came out. He seemed more concerned with learning and applying the procedures for doing the various tests. ~I attended his presentation in Amsterdam and I did not feel it was inappropriate. Because of time limitation, he went over the 11111111111111111111111111 'liiiillllill 5571095.0466.015 AI
About this Item
- Title
- Statement of John F. Brundage, M.D.
- Author
- Brundage, John F.
- Canvas
- Page 1
- Publication
- 1992-12-08
- Subject terms
- testimonies
- Series/Folder Title
- Government Response and Policy > Law > gp160 trials and controversy > Investigation of U.S. Department of Defense AIDS researchers
- Item type:
- testimonies
Technical Details
- Collection
- Jon Cohen AIDS Research Collection
- Link to this Item
-
https://name.umdl.umich.edu/5571095.0466.015
- Link to this scan
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https://quod.lib.umich.edu/c/cohenaids/5571095.0466.015/1
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Related Links
IIIF
- Manifest
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https://quod.lib.umich.edu/cgi/t/text/api/manifest/cohenaids:5571095.0466.015
Cite this Item
- Full citation
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"Statement of John F. Brundage, M.D." In the digital collection Jon Cohen AIDS Research Collection. https://name.umdl.umich.edu/5571095.0466.015. University of Michigan Library Digital Collections. Accessed June 10, 2025.