[Letter to Donna Shalala from Sidney M. Wolfe and Peter Lurie]

Effect of Duration of AZT Therapy on Infant Infections *
Data from ACTG 076

0
O'
It.. _
e __.s.al lsir+ +... -. s i i +- n.r i.i.. + ni '+.a r.rw b 1.. nr ri ir..

% Infants

infected with HIV

30
251
20
15
10
0-~

27.51

I

22.9.
I

I66A% fwer infections
7.7

tI
I
jS.I% "fewer inet
96
F.;~' ti
"n.

C
0
C)
N
4.
3..1
ID
to
I
2
x

N
a
C

22/96 infected._

16/58 infected

I LI Placebo
i!AZT

MM.-A.

-,

=/less than 12 weeks Greater than 12 weeks
(average=7 weeks) (average= 17 weeks)
Duration of Maternal AZT Therapy

* Data Presented by ACTG 074 researchers to
Data Safety M itorfrg Board, February, 1994

-

0