Department of Health and Human Services Public Health Service, Grant Application

GG Principal Investigator/Program Director (Last, flrst middle): Duesberg, Peter H.
a Source and cdentigng no. Council for Tobacco Research -- USA, Inc. #3057 p... Peter H. Duesberg
Title Retroviral Onc Genes and Cellular Proto One Genes
b. Your role on project Principal Investigator %Effort 25%
c. Dates and costs of entire project 07101193 - 06/30/96 $ 208,695 total costs
d. Dates and costs of current year 07/01/93 - 06/30/94 $ 69,565 total costs
e. Specific aims of project Structural and functional relationships between retroviral oncogenes and corresponding
cellular proto-oncogenes: Are mutated ("activated") proto-oncogenes carcinogenic? Generation of retroviral
oncogenes from proto-oncogenes and non-oncogenic retroviruses.
t Describe scientific and budgetary overlap Scientifically, the CTR and the interim NIH explore different aspects of the
same general topic. For instance, viral transduction of proto-onc gene-sequences and functional tests of mutated
proto-onc genes. There is no scientific overlap between them and the present application.
a Describe adjustments you will make if the present application is funded (budget,% effort, aims, etc.) Should the present application be
funded, Ruhong Li's effort on the CTR would be reduced to 0%, and we would hire areplacement postdoctoral
bo te on at 5 perform the duties originally designated for him.
c. Dates and costs.f.ent.re..r.je.t.0/01/9..-.06/.0/96.$.08,695.t.tal.cost

Name Peter H. Duesberg
a Source and identifying no. T
Title none

Active

Pendng X None
P.I. Peter H. Duesberg

he Randolph Foundation

b. Your role on project Principal Investigator % Effort 5%
c. Dates and costs of entire project 09/93-indef $65,944 total costs **
d Dates and costs of current year 09/93-indef $65,944 total costs **
e Specific aims of project This award is for "general support" of the research laboratory of Professor Duesberg.
Although funds for the award have not yet been received, pending negotiation of indirect cost rate,
a committment has been made to Professor Duesberg by the Foundation.
f. Describe scientific and budgetary overlap The funds for this award are for "general support"' of the laboratory, rather
than for a specific research project. None of the personnel listed in the present application will be supported from
Randolph Foundation funds.
g. Describe adjustments you will make if the present application is funded (budget, % effort, aims, etc.) None
PHS 398 (Rev. 9/91) (Form Page 7) Page 1 8 GG

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