Scientists Discover A Second Gene Alteration That Slows Progression to AIDS

"Just a few years ago, there was still quite a bit of discussion about whether genes could be
found that might explain the variable rates of progression to AIDS," said O'Brien. "Now we know there
are genes and that genetic approaches can play an important role in understanding HIV."
This work involved the cooperation of thousands of volunteers involved in five AIDS cohort
studies: Hemophilia Growth and Development Study, Multicenter AIDS Cohort Study. ALIVE Study,
Multicenter Hemophilia Cohort Study, and San Francisco City Cohort. These cohorts are supported by
various NIH institutes including the National Institute of Allergy and Infectious Diseases, the
National Cancer Institute, and the National Institute of Child Health and Human Development.
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