CCR5 Ligands in HIV Vaccines

References. 1. Cocchi F, DeVico AL, Garzino-Demo A, Arya SK, Gallo RC, Lusso P: Identification of RANTES, MIP-ic, and MIP- 1 3 as the major HIV-suppressive + factor produced by CD8 T cells. Science 270:1811-1815, 1995 2. Lehner T, Wang Y, Cranage M, Bergmeier LA, Mitchell E, Tao L, Hall G, Dennis M, Cook N, Brookes R, Klavinskis L, Jones I, Doyle C, Ward R: Protective mucosal immunity elicited by targeted iliac lymph node immunization with a subunit SIV envelope and core vaccine in macaques. Nat Med 2:767-775, 1996 3. Lehner T, Wang Y, Cranage M, Bergmeier LA, Mitchell E, Tao L, Hall G, Dennis M, Cook N, Jones I, Doyle C: Protective mucosal immunity elicited by targeted lymph node immunization with a subunit SIV envelope and core vaccine in macaques. Dev Biol Stand 92:225-235, 1998 4. Wang Y, Tao L, Mitchell E, Bogers WM, Doyle C, Bravery CA, Bergmeier LA, Kelly CG, Heeney JL, Lehner T: Generation of CD8 suppressor factor and beta chemokines, induced by xenogeneic immunization, in the prevention of simian immunodeficiency virus infection in macaques. Proc Natl Acad Sci U S A 95:5223 -5228, 1998 5. Heeney JL, Teeuwsen VJ, van Gils M, Bogers WM, De Giuli Morghen C, Radaelli A, Barnett S, Morein B, Akerblom L, Wang Y, Lehner T, Davis D: 13-chemokines and neutralizing antibody titers correlate with sterilizing immunity generated in HIV-1 vaccinated macaques. Proc Natl Acad Sci U S A 95:10803-10808, 1998 6. Ahmed RK, Nilsson C, Wang Y, Lehner T, Biberfeld G, Thorstensson R: f3 -chemokines in macaques vaccinated with live attenuated virus correlates with protection against SIVsm challenge. J Gen Virol 80:1569-1574. 7. Zagury D, Lachgar A, Chams V, Fall LS, Bernard J, Zagury JF, Bizzini B, Gringeri A, Santagostino E, Rappaport J, Feldman M, O'Brien SJ, Burny A, Gallo RC: C-C chemokines, pivotal in protection against HIV type 1 infection. Proc Natl Acad Sci U S A 95:3857-3861, 1998 8. Paxton WA, Liu R, Kang S, Wu L, Gingeras TR, Landau NR, Mackay CR, Koup RA: Reduced HIV-1 infectability of CD4+ lymphocytes from exposed-uninfected individuals: association with low expression of CCR5 and high production of f3 -chemokines. Virology 244:66-73, 1998. 9. Paxton WA, Martin SR, Tse D, O'Brien TR, Skurnick J, VanDevanter NL, Padian N, Braun IF, Kotler DP, Wolinsky SM, Koup RA: Relative resistance to HIV-1 infection, of CD4 lymphocytes from persons who remain uninfected despite multiple high-risk sexual exposure. Nat Med 2:412-417, 1996 10. Furci L, Scarlatti G, Burastero 5, Tambussi G, Colognesi C, Quillent C, Longhi R, Loverro P, Borgonovo B, Gaffi D, Carrow E, Malnati M, Lusso P, Siccardi AG, Lazzarin A, Berefta A: Antigen-driven C-C chemokine-mediated RNV-i suppression by CD4(+) T cells from exposed uninfected individuals expressing the wild-type CCR-5 allele. J Exp Med 186:455-460, 1997. 10

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Title
CCR5 Ligands in HIV Vaccines
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Garzino-Demo, Alfredo
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"CCR5 Ligands in HIV Vaccines." In the digital collection Jon Cohen AIDS Research Collection. https://name.umdl.umich.edu/5571095.0230.031. University of Michigan Library Digital Collections. Accessed May 11, 2025.
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