Abstract Book Vol. 2 [International Conference on AIDS (14th: 2002: Barcelona, Spain)]

XIV International AIDS Conference

Abstracts WePeF6662-WePeF6666 251

WePeF6662 The Study of Chinses herbal Formula "Qian Kun
Ning" treated HIV infectious following up to
33months
S.T. Yue. professor, 3# Third Lane Xiaojiacun, North Renmin Road, Institute of
Blood Transfusion, Chinses Academy of Medical Sciences, China
Background: Qian-Kun-Nin is a Chinese herbal medicine formulation of forteen
herbs. Data from a 18 months' investigation presented in XIII AIDS International
Conference show that Qian-Kun-Nin has significant activity on HIV growth inhibition and raising CD8 lymphocytes in vivo. To investigate long time effect of the
formula,the study has been followed up to 33 months.
Subjects and methods: We conducted this study to evaluate the anti-retroviral
and immunological enhancing effects of this formula on HIV positive subjects.
21 subjects completed the study and they recieved oral Qian-Kun-Nin capsules
3times per day for 33 months in a single blind design. Viral laoding determination with bDNA quatity method with Quatiplex system 2.0 and 3.0(Chiron and
Bayer,USA), lymphocytes surface antigen assay with Flowcytometer(FACScan
B-D USA).AII data were statistic with bifactors square analysis compared to the
baseline level.
Results: The plasma viral laoding decreased significantly at the end of 24th
month(p<0.05), however reincreased from 27th-33th months, but value of viral
loading at 33th monthis is still lower than base line(3.7768:4.1917). CD8 lymphocytes increased curve was similar as viral loading decreased(P<0.05) but CD4
lymphocytes was graduately decreased.
No any adverse effects were observed, and no significant side effects were
recorded in any subjects. These data suggest that Qian-Kun-Nin has therapeutic
potentiality in 1.5-2 years, especially it could be used in interval of discontinous
HAART therapy as an assistant drug.
Presenting author: Shitao Yue, 3# Third Lane Xiaojiacun, North Renmin Road,
Institute of Blood Transfusion, Chinses Academy of Medical Sciences, China, Tel.:
[phone], Fax: [phone], E-mail: [email protected]
WePeF6663 Barriers to adherence to an individualized fitness
regimen in an identified population of HIV+
patients
J.M. Fritsche, J.N. Gross, H.A. Kessler. Rush Presbyterian St. Luke's Medical
Center, 1604 Mandel Ave, Westchester, IL, 60154, United States
Issues: HIV infection can be associated with changes in body habitus, as a result
of wasting or lipodystrophy, which are often distressing to patients. Regular exercise is an important adjuvant in the care of persons with HIV and may mitigate the
effects of body habitus changes and result in improvements in body image and
mood.
Description: The Infectious Diseases Clinic at Rush initiated a free fitness program for patients with HIV/AIDS, which was developed by a certified trainer who
is a long-term HIV survivor. Consultations include an exercise history and fitness
survey The program was initiated in June, 2000. As of June, 2001, 55 out of a
pool of 600 patients expressed initial interest. Of these 55, only 19 (34%) completed a consultation, with only 4 (7%) of these adherent to a fitness regimen at
6 months. To determine the reasons for the low adherence rate, the fitness data
were evaluated. Patient demographics reveal 17 are male, 11 Caucasian, 2 Hispanic, 5 African American, 1 Asian, mean age is 46, mean Karnofsky is 96, 6 are
CDC Class A, 7 are B, 6 are C. All 19 patients surveyed rated improved mood as
"important", with 14 of 19 (74%) rating it as the "most important" reason to exercise, which may suggest an increased prevalence of mood disorders among our
patients. Based on this, the fitness survey was modified to capture more feelingsrelated information and the Beck Depression Inventory-Fast Screen was added.
The original respondents are currently being reevaluated with this revised questionnaire.
Lessons: Provision of free services does not guarantee patients' participation.
Understanding barriers to participation and adherence is vital to the development
of useful programs. Preliminary evaluation suggests that underlying mood disorders could be a barrier to adherence.
Recommendations: More research is needed to determine the effect of mood
disorders on participation in and adherence to a fitness program in HIV infected
patients.
Presenting author: Janice Fritsche, 1604 Mandel Ave, Westchester, IL, 60154,
United States, Tel.: [phone], Fax: [phone], E-mail: jfrits@rush.
edu
WePeF6664 Acupuncture is associated with greater
self-reported adherence to antiretroviral therapy
N. Robinson, P.J. Franks, H.P Loveday, C.M. Pellowe, C. Loveday, R.J. Pratt.
Thames Valley University, richard wells research centre/centre for
complementary therapies, thames valley university, 32-38 uxbridge road, london,

United Kingdom
Background: Estimates suggest 73% of HIV infected people are using Complementary and Alternative Medicine (CAM) to relieve their symptoms, including
those associated with antiretroviral therapy (ART). This study explored the hypothesis that those who used CAM would be more adherent to ART.
Methods: 222 clients attending 9 hospital HIV outpatient clinics in England were
interviewed. Self reported adherence to antiretroviral therapy was measured by

Morisky Medication Scale (MMAS), Reported Adherence to Medication scale
(RAM).
Results: Of the 73 respondents who reported using CAM, 22% (35) used them
regularly and 24% (38) used them occasionally. Therapies which entailed a
visit to a complementary therapy practitioner were reported by 58% (42) clients.
Acupuncture and aromatherapy were those most frequently accessed 15% and
14%, followed by reflexology and massage, 12% respectively. Self-medication using herbs or vitamins was practised by nearly two thirds of clients, either regularly
or occasionally. Fifteen clients were using multiple therapies. Self reported adherence to antiretroviral therapy was compared for those using complementary
therapies and those who did not. Analysis of the individual therapies identified
that acupuncture was the only individual complementary therapy showing a significant correlation with adherence (MMAS r = -0.247, p=0.003, RAM r = 0.227,
p=0.003).
Conclusion: Acupuncture may be associated with greater adherence to ART but
there was no overall, association between adherence and those respondents who
used CAM in addition to their antiretroviral therapy. Further research on individual
therapies need to be conducted with larger cohorts.
Presenting author: nicola robinson, richard wells research centre/centre for
complementary therapies, thames valley university, 32-38 uxbridge road, london,
United Kingdom, Tel.: [phone], Fax: [phone], E-mail: nickyrobinson
@tvu.ac.uk
WePeF6665 Realities, hopes and challanges for traditional
herbal thearpies in management of oppurtunistic
infections in HIV/AIDS patients in Uganda
W. Aryeiia1, Y.H. Sekagya2, F. Nakibuka3, E. Bitwari 2. 1Po Box 16465,
Kampala, Uganda; 2 Seya nursing home/Prometra, Kampala, Uganda;
3 Prometra, Kampala, Uganda
Issues: Herbal Medicine is a major healthcare strategy in care, management,
support and prevention of HIV/Aids in the developing world. Herbal therapy can
manage most opportunistic infections in HIV/Aids patients. After several years of
usage, utilization of herbal medicines for HIV/Aids patients, herbalists have given
relief and hope for many HIV/Aids patients in the developing countries where
there are:
- High incidences of HIV/Aids cases and infections.
- High (prohibitive) costs and scarcity of medical services and anti retrovials.
- Alarming attrition of medical staff secondary to HIV/Aids related illnesses is
further weakening the health system and capacity to provide services.
- Intermittent availability of medical services for the majority poor people.
Current herbal therapies, experiences and innovations, advances, trends and
constitution for HIV/AIDS patients should be known, tested and applied.
Description: This paper will analyze the various integrated systematic herbal
therapeutic practices, philosophies and methodological approaches for caring,
management and support for HIV/Aids patients and herbalists and empowerment
of herbalists to better manage opportunistic infections in HIV/AIDS patients. It
also analysis realities, challenges in a hospice that has endeavored in providing
herbal therapies in care and managerial aspects support, education, counseling,
outreaches and systemic herbal Medicare for HIV/AIDS patients.
This paper is based on personal experiences within a professional role as a medical sociologist and community healthworker with a hospice engaged in herbal
therapy and community healthcare support for people living with HIV/Aids and
herbalists providing care and support for HIV/Aids patients-SEYA NURSING
HOME in Uganda -Africa.
Lessons learned: A hospice engaged in Herbal therapy and integrated
tradimedicare systemic practices for caring, management and support of people living with HIV/Aids in collaboration with herbalist has resulted in a clear and
effective ways to access, care, educate, and support for the majority vulnerable
people living with HIV/Aids in a developing country
Recommendation: This Project/research recommends that herbal therapy practice and appropriate traditional medicine models and systems be established,
adopted, harnessed and applied in caring and supporting people living with
HIV/Aids in developing countries.
Presenting author: Warren Aryeija, Po box 16465, Kampala, Uganda, Tel.: +256
41 567652, E-mail: [email protected]
WePeF6666 Determinants of complementary therapies (CT)
use in People Living with HIV (PLWHIV)
P. Nasta1, V. Agnoletto2, F. Chiaffarino3, F. Parazzini3, G. Weler4,
M. Marienne5, Y Behar6. of Infectious and Tropical Diseases, Brescia,
Italy; 2L/LA-Italian League for fighet against AIDS, Milan, Italy; 3Mario Negri
Institute, Milan, Italy; 4Deutsche AIDS Hilfe, Institute of Infectious and Tropical
Diseases, Germany; 5HIV Associations, Brusselles, Belgium; 6Action Traitment,
Paris, France

Background: CT has expanded rapidly in the recent years, the motivations of
use CT are complex and differ from country and from the HAART era respect
pre HAART era. ELECTHIV project (European Level Evaluation of Complementary Techniques in HIV), promoted by EU and Italian Institute of Health, analysed
the determinants of CT use among PLWHIV attending ONG against AIDS in 7
different European country in the HAART era.
Aims: ELECTHIV is a case control study comparing the ever CT and never CT