Abstract Book Vol. 2 [International Conference on AIDS (14th: 2002: Barcelona, Spain)]

XIV International AIDS Conference Abstracts WePeC6096-WePeC6099 107 rates were higher among pregnant women (42.2%) than female VCT clients (30.9%) (P<0.001). The same trend was observed in age groups 15-19 years (27% vs 9%) and 20-29 years (44.7% vs 31.7%). Single women had higher HIV+ rates than married women both among pregnant women (42.7% vs 34.9%) and among female VCT clients (31.5% vs 25.7%). Women without formal education or who completed only primary school were more likely to be HIV+ than those who completed secondary or those with tertiary education (pregnant women: 45.9%, 40.8%, 29.2%; VCT clients: 54.7%, 34.2%, and 16.2%, test for trend, P<0.001). Women with a regular job were more HIV+ than women without a job both for pregnant women (46.2% vs 39.8%) and VCT clients (32.2% vs 29.4%). Conclusions: Although HIV prevalence estimates using pregnant women were higher than those using female VCT clients, both programs yield data that show similar trends. In Botswana, HIV infection among women is associated with age, single status, education, and disposable income through employment. Presenting author: Thierry Roels, The BOTUSA Project/CDC, PO Box 90, Gaborone, Botswana, Tel.: +267 301 696, Fax: +267 373 117, E-mail: tbr6@cdc. gov WePeC6096 Antenatal Clinic National HIV Surveillance in Mozambique: Variation in prevalence underscores different epidemics in the country P.A. Noya1, I.A. Nhatave1, H. Tojais2, S. Stakteas3, K. Foreit4, A.E. Vergara5, A. Barreto6. 'Dept. of Epidemiology and Endemic Disease, Ministry of Health, Mozambique, Maputo; 2The Futures Group International, Maputo; 3National Institute of Health, Ministry of Health, Mozambique, Maputo, Mozambique; 4 The Futures Group International, Washington, United States; 5Global AIDS Program, Centers For Disease Control and Prevention, Mozambique, Maputo; 'National Directorate of Health for Epidemiology and Environmental Health, Ministry of Health, Maputo, Mozambique Background: Previous to 2000, Mozambique had only four sentinel sites (SS). None were located in the northern region, nor in rural areas. Realizing these shortcomings, in 2000, the Ministry of Health decided to increase the number of sites to 22 and distribute them across all eleven provinces in both rural and urban areas to improve the national picture of the epidemic. Methods: Sentinel HIV surveillance in Mozambique uses the anonymous, unlinked methodology and is carried out in antenatal clinics. In 2000, quality control was instituted at the central level, and supervisory visits increased. Data presented here are from 20 sites, the remaining two were excluded because of operational and quality control problems. Province-specific prevalence rates were calculated by assigning each district to a SS, using that site's prevalence, and weighting by district population size. Assignment of districts to SSs was accomplished on the basis of social, economic, and cultural similarity between the SS and target districts. Results: Prevalence rates varied a great deal from province to province. The lowest rates occurred in the northern region ranging from 5 to 7%. In the southern region, rates ranged from 10 to 16%. Finally the highest rates were in the central region, ranging from 13 to 21%, with three of the four provinces showing prevalence around 20%. Conclusions: New data from the sentinel surveillance of HIV in Mozambique underscore the need to prioritize responses to the epidemic in different geographical areas. While prevention should still constitute a major effort in all areas, impact reduction needs to be considered more strongly in areas of higher prevalence, where the epidemic is probably of longer duration. Prevalence rates especially in the central and also in the southern regions call for increased resource allocation for care and support as well as other impact reduction interventions. Presenting author: Pedro Noya, PRO.Box 3652, Maputo, Mozambique, Tel.: +258 1 430970, Fax: +258 1 430970, E-mail: [email protected] WePeC6097 Reversal trends of HIV1 and HIV2 sero-prevalence among pregnant women, in four urban major areas in Senegal (1989-2001) P.M. Ndoye1, A. Gueye-Gaye', A. Gueye-Ndiaye', N.C. Toure-Kane', A. Gaye-Diallo', I. Ndoye2, S. Mboup1. 'Bacteriology-Virology Laboratory Dakar, Senegal; 2NACP, Dakar, Senegal Background: This study focuses on the course of the HIV epidemics in four urban areas Senegal. The prevalence of HIV1 and HIV2 has been evaluated through the National HIV Sentinel Surveillance Program since 1989. Methods: The HIV sentinel surveillance program includes regional laboratories collecting sera in sentinel sites and Virology Reference Laboratory of Le Dantec Hospital. Surveys are regularly done among pregnant women in four regions (Dakar, Kaolack, Ziguinchor and Thies) since 1989. A first screening of collected sera carried out at the regional laboratory and samples are sent to the reference laboratory for confirmation or discrimination and quality control. Basic epidemiologic measures of frequency are calculated with 95% CI and Mantel-Haenszel technique, is explored. Results: Since 1989 HIV1 and HIV2 prevalence were stable (c2trend=0.3, p=0.6) and (c2trend=0.7, p=0.4) among pregnant women in Dakar. Reversal progression trends have been observed since 1996. In 2001, the prevalence was 0.7%. In Kaolack, the higher prevalence areas HIV2 prevalence first stable, and then tended to decrease since 1999 whereas HIV1 increased. The HIV infection trend decreased with a prevalence of 0.8% in 2001. Conclusions: HIV1 prevalence increased significantly and the HIV2 prevalence was stable among pregnant women, The prevalence of HIV among pregnant women was maintained between 0.5 to 1.6% since the beginning of HIV infection in sentinel sites. Combined behavioral and biological survey among specific groups is undertaken to provide additional knowledge about HIV infection levels and risk behaviors to complement existing biological and behavioral surveillance activities. Presenting author: Papa Moussa Ndoye, 30 Avenue Pasteur, Po Box 7325, Dakar, Senegal, Tel.: +221 822 59 19, Fax: +221 821 64 42, E-mail: pmndoye @eci.harvard.edu WePeC6098 New diagnoses of HIV infection since 2000: Implications for primary prevention amongst gay and bisexual men in England and Wales N.D. Macdonald, J.Y. Mortimer, K.A. Fenton. PHLS HIV Reporting Centre at CDSC, London, United Kingdom Background: Surveillance of new diagnoses of HIV infections in the United Kingdom (UK) has recently been enhanced by the introduction of HIV reporting from Clinicians, who have been asked to report all adults diagnosed since January 2000. Prior to this, surveillance of new diagnoses has been through laboratory reports, and the extent of epidemiological information available to Microbiologists is often limited. With the decline in the number of AIDS cases reported since the introduction of HAART, the opportunity has been taken to request additional information from Clinicians. This report presents results from this enhanced surveillance relevant to primary HIV prevention amongst gay and bisexual men in England and Wales. Methods: Data on individuals exposed to HIV through sex between men and diagnosed since January 2000 in England and Wales and reported by December 2001 were analysed. Results: A total of 2393 individuals exposed to HIV through sex between men were diagnosed and reported between January 2000 and December 2001. Laboratory reports were received for 83%, Clinician reports 57%, with 40% both. Median age at diagnosis was 34 years (IQR 29-40). Country of probable infection was reported for 41%, for which 84% of whom it was the UK. Country of birth was reported for 53%, for 71% of whom it was the UK. 80% (1132/1419) were reported as either infected or born in the UK. Ethnicity was reported for 73%, of which 87% were white. A CD4 count around time of diagnosis was reported for 52%, with a median count of 355 cells/Rl (IQR 144-563). A previous HIV negative test was reported for 26% with 18% within 3 years of testing positive. Conclusions: Despite initial limitations in coverage and completeness of information this enhanced surveillance can identify groups within the potential remit of national primary prevention, whose characteristics, particularly where recently infected, can improve targeting of prevention efforts. Presenting author: Neil Macdonald, PHLS HIV Reporting Centre at CDSC, 61 Colindale Avenue, London, NW9 5EQ, United Kingdom, Tel.: +44 (0)208 200 6868, Fax: +44(0)208 7868, E-mail: [email protected] WePeC6099 Attendance to the AIDS information and prevention centre (CIPS) of Alicante (Spain) of users with 60 or more years J. Belda lbahez, E. Fernandez Garcia', R. Martinez Quintero', J. Trullen Gas2, M.G. Molina', R. Alonso1. 1CIPS (Centro de Informaci6n y Prevenci6n del SIDA), Plaza de Espaha 6, CIPS, Plaza de Espaia, 6, Alicante - 03010, Alicante, Spain; 2CIPS of Castellon, Castellon, Spain Background: The aim of this study was to know the HIV-related risk practices which tell the users with 60 or more years, and their relation with the prevalence of the HIV infection. Methods: Descriptive study of the users who attended for the first time the CIPS of Alicante from 1987 to 2001 and are 60 years old or more, analysing sociodemographic variables (age, sex), main risk practice and HIV as a result variable. We included the data in a Dbaselllplus database and analysed it with the statistical program Epilnfo-Vl. Results: The number of clinical-epidemiological stories, which we analysed, was 151. The 72.8% of the users were male. The 54.3% were 60 to 64 years old and the 27.8% were 65-70. The 60.3% attended the centre because of heterosexual relations, being these users male in the 76.9% and females in the 23.1%. The 11.9% attended because of living together with HIV-positive persons, without significant genre differences in this group; the 11.9% were men who have sex with men (MSM) and the 14.6% attended for another reasons, without genre differences. HIV status: 139 (92.4%) were tested for HIV antibodies and 10 (7.2%) turned out to be positive, 8 (7.8%) males and 2 (4.9%) females. In the positive group, 2 men reported Injecting Drug Use (IDU), 3 men sexual relation with other men, 3 male heterosexual relation and the 2 women presented seropositive sexual partner (one of them IDU). Conclusions: In spite of the little representation of this age group in the total number of the CIPS' users, (about 1%), we think the seropositivity percentage (7.8%) of those who attended, not been representative, is important and we believe that it must be a line of work to do approach information about the HIV infection and STD, as well as about the resource. Presenting author: Josefina Belda lbahez, CIPS, Plaza de Espafia, 6, Alicante

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Abstract Book Vol. 2 [International Conference on AIDS (14th: 2002: Barcelona, Spain)]
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International AIDS Society
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Page 107
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2002
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abstracts (summaries)
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