The New Joint Guide for the Use of Antiretroviral Treatments in Resource Limited Settings Presented Today

However, there is evidence that in patients with advanced HIV disease who are at high
risk of progression, dual nucleoside regimens produce some benefit even though they
cannot achieve or sustain suppression of HIV replication to the same extent as the threedrug regimens. Despite this limitation, where a more potent regimen is not available, 2
nucleoside reverse transcriptase inhibitors may be suitable for use in resource limited
settings.
"Research is vital to inform future treatment and care decisions as well as for the
advancement of scientific knowledge," said Stefano Vella, IAS, and added "to date there
has been a paucity of controlled clinical trials conducted in low and middle-income
countries." "It is also of paramount importance that countries design information and
training plans as an integral part of ART programs," said Paula Munderi, WHO. "This is
why the joint guide defines suitable topics for research and information and training
needs for resource limited settings," concluded Mark Wainberg, IAS.