Bridging the Gap: Conference Record [Abstract book, International Conference on AIDS (12th: 1998: Geneva, Switzerland)]

936 Abstracts 43460-43464

12th World AIDS Conference

0.63%; 9.3 ~ 2.2%; 27.5 ~ 7.2%; Dali city (1992-1996): 0; 0; 0; 4.7 ~ 2.3%;
47.5 ~ 15.5%; Kaiyuan city (1992-1997): 0; 0; 0; 0.4 ~ 0.53%; 25.7 ~ 4.9%;
70.3 ~ 10.4%; Lincang county (1994-1997): 4.9 ~ 3.5%; 50.0 ~ 10.3%;75.0
~ 8.7%; 66.6 ~ 10.1%; Weishan county (1994-1997): 0; 0; 17.1 ~ 8.8%; 59.5
1 10.5%; Genma county (1992-1997): 0; 0; 10.0 ~ 18.6%; 0; 48.0 ~ 18.5%;
48.4 ~ 10.3%. 2. Gradually increasing type (2 sites): Luxi county (1992-1997):
2.0 ~ 3.8%; 0; 1.5 ~ 2.9%; 8.3 ~ 4.7%; 17.1 ~ 5.2%; 19.6 A- 15.4%; Baoshan
city (1992-1997): 0; 0; 0.6 ~ 0.8%; 0.4 ~ 0.6%; 2.4 ~ 1.7%; 9.6 ~ 4.1%. 3.
Stable high prevalence type (3 sites): Ruili county (1992-1996): 72.9 ~ 10.0%;
56.3 ~ 12.9%; 45.0 ~ 13.7%; 73.2 ~ 11.6%; 76.8 ~ 11.1%; Longchuan county
(1992-1997): 28.3 ~ 9.2%; 46.0 ~ 8.5%; 47.1 ~ 7.8%; 60.0 ~ 14.3%; 45.5 ~
9.8%; 56.6 ~ 12.5%;Yunjiang county (1992-1997): 12.8 ~ 9.57%; 22.2 ~ 15.6%;
35.3 ~ 10.2%; 30.0 ~ 14.2%; 31.7 ~ 14.2%; 40.8 ~ 13.8%.
Conclusion: HIV spread among IVDUs in Yunnan Province has increased
rapidly since 1995. HIV infection caused by IVDUs is serious in Yunnan. The
estimated number of HIV positive IVDUs in Yunnan Province was 25,000-30,000
by 1997. It is urgent to take action to control HIV/AIDS among IVDUs.
143460 1 HIV, AIDS and STD database in use for the Western
Pacific region
Annette Ghee, S.O. Omi, N.F. Fee, G.P. Poumerol. World Health Organization,
P O. Box 2932 1000, Manila, Philippines
Issues: In this era of rapid information exchange, epidemiological information
should be easily available in a form that is useful for public health action. HIV,
AIDS and STD epidemiological information needs to be managed and stored so
that it is available for easy analysis and use.
Project: The WHO Office for the Western Pacific (WPR) collects, analyses and
disseminates epidemiological information on HIV, AIDS and STDs from 36 Member States. Over the past year, WPR has developed and tested a user-friendly
database (MS Windows-based) to store and manage this data. This database is
regularly updated with official, published and unpublished reports. Data cleaning
and referencing of source documents is a continuing process.
Results: The database is now operational. "Read only" access is available
through the WHO WPR home page (www.who.org.ph). Users can breakdown
available data in various ways (e.g. sex, age group, transmission risk category)
to quickly generate standardized reports. Users can also develop customized
presentations by downloading data as an MS Excel spreadsheet. Users also
can compare data within the database (e.g., over time or between countries),
or to new information. WPR has already used the database to prepare regional
epidemiological profiles (including estimates) for HIV, AIDS and selected STDs.
And it is planned that Member States will eventually report their HIV, AIDS and
STD data to WHO through the data base.
Lessons learned: The database has been well received by epidemiologists
from within and outside WPR. With slight adaptation, the database can be used
at the national level. Easy access to a wide range of epidemiological information
will enable public health professionals to improve the quality of their interventions
and reports.
43461 Reporting system, surveillance of HIV/AIDS and analysis
of data
Gupta Avdhesh1, N.M. Singhvi2. 1D-32 Chikitsalaymarg, Bapunagar Jaipur
302015; 2Medical and Health Services, Jaipur, Rajasthan
Objectives: To find out HIV +ve incidence in different age, sex & other groups in
the present reporting system along with common presenting symptoms in AIDS
patients.
Design: Reports from all over state collected at State AIDS Cell.
Methods: A Surveillance centre established in state in the year 1987. In the
state 6 Zonal Blood Testing Centre, 34 Blood banks in districts and 5 blood banks
in the private sector are working. All testing centre sends the monthly report to
State AIDS Cell where they compiled and HIV positivity rate in different groups
calculated. Since 1987 total 3,49,637 blood samples screened for HIV and out of
that 1672 were positive. This year total no of screened samples is 72669 and out
of that positive samples were 374. Till know 58 full blown AIDS cases detected
in the state and out of that 30 patients were suffering from opportunistic infection
tuberculosis.
Results: In Rajasthan the HIV positivity rate is 0.47% only. The and for this year
the rate is slight higher 0.51%. At our surveillance centre this year till September
51% of patients were from 21 to 30 years of age group and 34% from the age
group of 31 to 40 years. Similarly in AIDS patients the maximum age group
affected is same as HIV positive group.
Conclusion: That it comfirms the international study that maximum age group
affected is from 21 to 40 years the age that is tender age for National Production
personnel. It further confirms that the most common opportunistic infection is
Tuberculosis

43462 Lessons learned on trends in HIV/AIDS sentinel
surveillance in Tanzania relying on constantly submitted
data
Paul Senge1, J.N. Ndyongeje2. 1PO. Box 11857 Dar Es Salaam; 2National AIDS
Control Programme, Dar Es Salaam, Tanzania
Background: Sentinel populations approved for HIV surveillance in Tanzania

include pregnant women and blood donors. Established in 1990, todate a total
of 24 sentinel sites are operational, initiated in 11 out of the 20 regions in the
country.
Method: All pregnant women attending a clinic for the first time during any
pregnancy constitute the sentinel surveillance data population. The women are
provided with routine ante-natal care, and venous blood (5-10 mis), which is
routinely taken for ante-natal investigations, is utilized in testing and guiding
treatment for syphilis infection and anaemia. In addition, the same blood sample
is tested for HIV infection in such a way that results cannot be traced back to
the individual women, i.e. the testing is anonymous and data are permanently
unlinked. The sampling technique of the blood specimens is sequential is nature,
whereby the first 300 specimens are selected for HIV testing. Since 1990 all the
182 hospitals in the country have been screening blood from donors to ensure
safe transfusion.
Results: The prevalence of HIV infection among women attending various
ante-natal clinics are as shown:- 1994: 5.1%-27.5%; 1995: 0%-32.5%; 1996:
5.5%-23.1%. The prevalence of HIV-1 infection among blood donors by region
and by sex between 1987 and 1996 ranges from 3.0% to 17.2% among males and
3.2 to 14.9% among females. Since 1989 prevalence rates seem to be declining
slowly. The average figures were 8.2% for females and 6.1% for males between
1994 and 1996.
During 1994, 8.3% of all reported AIDS cases were observed to be due to
mother to child transmission, while in 1995 it was up to 9.8% and during 1996 it
was 3.6%.
Conculusion: Assuming a constant decline in prevalence of HIV infection in
pregnant women and their offsprings over time, indicates success in advocacy and
full commitment at all levels. Interventions at District AIDS Control Programme
need be intensified, especially in urban settings. Young pregnant women seem
to represent a group with young increased high risk behaviour
43463 Quality assurance program for plasmatic viral load of
HIV-1 by NASBA technology in 32 laboratories located in
Brazil
Claudia Martins Renata1, M. Franchini2, M.C. Dantas2, Y. Bravim3, A.M.S. De
Araujo3, J.M. Batista4, A. Tanuri5. 1Esplanada Dos Ministerios-Ministerio DA
Saude-BL. G Sobreloja-115 Brasilia DF,; 2Ministry of Health, Brasilia DF,;
3Laboratorio Central Noel Nutels, Rio De Janeiro RJ,; 4Jorge Moreira, Rio
Janeiro RJ,; 5 Universidade Federal Do Rio De Janeiro, Rio De Janeiro, Brazil
70058-900
Issue: A quality assurance program is of critical importance to evaluate the
performance of HIV-1 viral load laboratories network in Brazil.
Project: In March of 1997, the Brazilian National Programme on Sexually
Transmitted Diseases and AIDS, from the Ministry of Health, came to the conclusion that patients under combined anti-retroviral therapy might be monitored
on the plasmatic levels of viral RNA so as to evaluate the efficacy of therapy.
To achieve this objective, a vital load laboratory network consisting of thirty five
laboratories was implemented. The technology being used in all laboratories
is NASBA. In order to evaluate the performance of the laboratories, a Quality
Assurance Program was established. The panel for proficiency consisted of 3
samples containing 100,000 copies of RNA per ml (5.00 log1o), 10,000 copies
per ml (4.00 log1o) and one negative control.
Results: From 35 laboratories that received the panel, 32 performed the tests.
The average of viral load obtained for the 5.00 loglo sample (control 1) was
4.97 ~ 0.17 and for the 4.00 loglo sample (control 2) was 4.11 ~ 0.28. All the
laboratories had results lower than 400 copies for the negative control. These
data suggest that the control 2 has higher standard deviation than the control 1.
Statistical analysis are being carried out to evaluate the performance of individual
laboratories.
Lessons Learned: By using NASBA technology, it was verified that samples
with viral load of 4.00 logio have higher standard deviation than samples with 5.00
logio. A Quality Assurance Program is of considerable importance to evaluate
the performance of the Brazilian viral load laboratories network.
143464 Development of a follow-up system with regard to
HIV/AIDS patients care
Anibal Henriquez1, F. Trujillo1, G. Berrios1, R. Child1, L. Toro1, M. Pino2.
1Comision Nacional Del Sida, Santiago; 2Programmer's House Chile Ltd A.,
Santiago, Chile
Introduction: In order to improve the quality of the clinical care of HIV/AIDS
patients, quantify the economic impact of the epidemic in the area of public health
and contribute to the equity in the assignation of resources, an information system
has been developed that makes easier the action of the Chilean Ministry of Health
and the public hospitals.
Objectives: - Incorporate the health care teams to efficient management processes by means of introducing them to updated information technology. - Specify
individual clinical evolution of the sickness. - Evaluate individual and global care

expenses in each care centre included in the project. - Deliver structured data
on the clinical, epidemiological and economic areas.
Materials and Methods: Through the work of a multidisciplinary team a software was developed. In this initial experience the system was installed in two
hospitals, projecting offering it to the 14 more important hospitals of the country in
a subsequent stage. The software is designed with an approach of relational data
base in Windows 95 and allows data acquisition on real time. The transference