Final Program and Oral Abstracts [International Conference on AIDS (8th: 1992: Amsterdam, Netherlands)]

SESSIONS

THURSDAY, 23 JULY 1992 16.15-17.45

SESSION 177

SESSION 178

Thursday, 23 July 1992
Time: 16.15-17.45
Lecture room: Al
Session title: ANTIVIRAL DRUG RESISTANCE
Oral Abstract
Chairperson: Douglas Richman (UNITED STATES)

Thursday, 23 July 1992
Time: 16.15-17.45
Lecture room: A2
Session title: EPITOPES OF T-CELL IMMUNIT
Oral Abstract
Chairperson: Jean-Paul Levy (FRANCE)
Abstract #

Abstract #

14.30
FUNCTIONAL ANALYSIS OF HIV TYPE 1 REVERSE
TRANSCRIPTASE RESISTANCE TO DIVERSE
NONNUCLEOSIDE INHIBITORS
Emini, Emilio A.*; Sardana, V.V.*; Byrnes, V.W.*;
Register, R.B.*; Schleif, W.A.*; Condra, J.H.*; *Merck,
Sharp and Dohme Research Labs.; West Point;
UNITED STATES
14.40
IDENTIFICATION AND SIGNIFICANCE OF A FIFTH
MUTATION IN HIV-1 REVERSE TRANSCRIPTASE
CONTRIBUTING TO ZIDOVUDINE RESISTANCE
Kellam, Paul*; Larder, B.A.*; Boucher, C.A.**; *The
Wellcome Research Laboratories; Beckenham;
UNITED KINGDOM; **Academic Medical Centre,
University of Amsterdam; Amsterdam; NETHERLANDS
14.50
DIDEOXYNUCLEOSIDE RESISTANCE PATTERNS IN
CLINICAL ISOLATES OF HIV-1
McLeod, Gavin*; Mayers, D.**; McCutchan, F.**;
Sanders-Buell, E.**; Hammer, S.*; *New England
Deaconess Hospital and Harvard Medical School;
Boston; UNITED STATES; **Walter Reed Army Inst. of
Research; Washington
15.00
NOVEL MUTATION SITES IN THE REVERSE
TRANSCRIPTASE (RT) SEQUENCE OF AZT RESISTANT
HIV-1 MAP TO THE ACTIVE SITE OF AN RT MODEL
Levantis, Petros*; Stein, C.A.*; Lindborg, B.**;
Broadhurst, K.*; Oxford, J.S.*; *London Hospital
Medical College; London; UNITED KINGDOM;
**Medivir; Huddinge; SWEDEN
15.10
EVOLUTION OF ZIDOVUDINE RESISTANT HIV-1
ISOLATES ASSESSED BY CLONAL ANALYSIS
Tijnagel, Jolanda*; Kellam, P.**; Larder, B.**;
Boucher, C.*; *University of Amsterdam; Amsterdam;
NETHERLANDS; **Wellcome; Beckenham; UNITED
KINGDOM
15.20
DISCUSSANT
Crumpacker, Clyde; Beth Israel Hospital; UNITED
STATES

16.15
ThA 1567 HETEROGENEITY OF T CELL RECOGNITION OF THE
SIV ENVELOPE GLYCOPROTEIN
Jones, Wendy*; Barnard, A.*; Slade, A.*; Mills,
K.H.G.*; *National Institute for Biological Standards &
Control; South Mimms; UNITED KINGDOM
16.25
ADOPTIVE TRANSFER OF A NEF-SPECIFIC CTL
CLONE INTO hu-PBL-SCID MICE AND AN HIVThA 1568 INFECTED PATIENT
Koenig, Scott*; van Kuyk, R.**; Jones, G.***; Torbett,
B.**; Mosier, D.**; Brewah, Y.A.*; Leath, S.*; Et AI.;
*Medimmune, Inc.; Gaithersburg; UNITED STATES;
**MBI; LaJolla; ***NIAID; Bethesda
16.35
IDENTIFICATION OF CYTOTOXIC T LYMPHOCYTE
EPITOPES AND ANALYSIS OF SEQUENCE VARIATION
ThA 1569 IN A LABORATORY WORKER INFECTED WITH HIV-1
IIIB
Johnson, Paul R.*; Trocha, A.*; Dynan, M.*; D'Aquila,
R.*; Blattner, W.**; Walker, B.D.*; *Massachusetts
General Hospital; Boston; UNITED STATES; **NCI,
NIH; Bethesda
16.45
LIMITED T-CELL RECEPTOR GENE USAGE IN HIV-1
ThA 1570 ENVELOPE SPECIFIC CYTOTOXIC T-LYMPHOCYTES
FROM AN INFECTED INDIVIDUAL
Kalams, Spyros*; Johnson, R.P.*; Trocha, A.*; Dynan,
M.*; Kurnick, J.T.**; Walker, B.D.*; *MA General
Hospital, Infectious Disease Unit; Boston; UNITED
STATES **MA General Hospital, Dept. of Pathology
16.55
CHARACTERISATION OF SEVERAL PROMISCUOUS
ThA 1571 CTL EPITOPES IN THE C-TERMINAL REGION OF NEF
Hadida, Fabienne*; Samri, A.*; Hosmalin, A.*; Spohn,
R.**; Jung, G.**; Debre, P.*; Autran, B.*; *Hopital
Pitie-Salpetriere; Paris; FRANCE; **Eber. Karls
University; Tuebingen; GERMANY

ThA 1572
ThA 1573
ThA 1574
ThA 1575
ThA 1576

17.05
DISCUSSANT
Walker, Bruce; Massachusetts General Hospital;
UNITED STATES

229