Reports on HIV/AIDS: 1990

JANUARY 26, 1990, MMWR, Vol. 39, RR-1: [inclusive page numbers]
Information is collected on the following:
* circumstances associated with exposures
* extent to which zidovudine and other antiretroviral agents are prescribed for
postexposure chemoprophylaxis, including dosage and timing
* incidence of associated toxicity
* rate of HIV seroconversion among workers who do and do not receive postexposure chemoprophylaxis
All physicians who provide care to a worker within 1 month after an occupational
exposure to HIV, regardless of whether an antiretroviral agent is prescribed, are
encouraged to enroll the worker in the CDC surveillance system. Enrollment and
follow-up requirements have been simplified; in particular, it is no longer necessary
to send blood specimens to CDC for HIV serologic testing unless the enzyme
immunoassay (EIA) performed by a licensed local laboratory is reactive or equivocal.
CDC will continue, however, to offer EIA testing at no charge on specimens from
surveillance participants on request. Additional information and enrollment materials
can be obtained from the Hospital Infections Program, Center for Infectious Diseases,
Centers for Disease Control, Mail Stop C-10, Atlanta, GA 30333; telephone (404)
639-1644.

CONTACTS FOR PHYSICIANS AND FOR INFECTION
CONTROL AND OCCUPATIONAL HEALTH PROFESSIONALS
* To enroll persons who have had a "massive exposure" to HIV in NIAID study
of zidovudine prophylaxis, telephone [phone].
* To report adverse effects associated with zidovudine to FDA, use "Adverse
Reaction Report" forms (FDA #1639), obtainable from:
Food and Drug Administration
Office of Epidemiology and Biostatistics
HFD-730
Rockville, MD 20857
[phone].
* To enroll an exposed worker in the CDC prospective surveillance system,
telephone [phone].
* To enroll pregnant women who receive zidovudine during pregnancy,
contact:
Zidovudine in Pregnancy Registry
Epidemiology, Information, and Surveillance Division
Burroughs-Wellcome Company
3030 Cornwallis Road
Research Triangle Park, NC 27709
[phone] (collect) or [phone].

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