A Guide to Fiscal Year 1991 Federal Funding for HIV Disease: How Dollars are Spent How to Access Them

groups for infection; incidence and prevalence of immune deficiencies and infectious disease among
alcohol abusers and alcoholics; and effects of
primary/secondary psychiatric disorders among
seronegative alcoholics and alcohol abusers at risk
for HIV infection because of self-destructive
behaviors.
* Behavioral and psychosocial aspects of HIV and
AIDS, including: alcohol influence on the interaction
of psychological and social variables that increase the
risk for HIV infection; effects of alcohol use by the
general population on judgment, decision-making,
perception of risk with respect to HIV infection, and
moral commitment to others; the function of alcohol
environments (such as singles or gay bars) as
facilitators or disincentives of AIDS-related, risktaking behavior; the role of alcohol consumption in
increasing risk-taking behavior which may enhance
the probability of HIV infection by exposure to other
high-risk sexual or drug abuse behaviors; alcohol use
as a mechanism to cope with high-risk or seropositive
status; and design and evaluation of intervention
strategies on seropositive individuals that would prevent alcohol-related behaviors that could result in
HIV infection of partners.
* Clinical research training on alcoholism in connection with the natural history and course of HIV
infection and AIDS, and on alcoholism and alcohol
abuse as a distinct factor in the diagnosis and treatment of AIDS encephalopathy.
* AIDS-related biomedical research related to the
role of alcohol in increasing host susceptibility to HIV
infection and in contribution to the progression of the
disease, including: direct or indirect effect of alcohol
on the mechanisms of infection by HIV and related
viruses in vivo and in vitro; development and use of
appropriate animal models to evaluate the effect of
acute and chronic alcohol administration in the different phases of HIV disease; the role of alcohol as
a cofactor in precipitating the development of AIDS
in seropositive individuals; the effect of alcohol on
the development of the immune system and on the
placental and lactational immune transfer; pathologic
alteration of genetic processes caused by alcohol that
could lead to altered immune response; alcoholinduced neuroimmune and neuroendocrine alterations as cofactors in HIV disease and AIDS; effect
of alcohol consumption on latent viral infections and
their association with HIV infection; function of
alcohol as a "triggering" mechanism in the development of HIV encephalopathy; and the effect of
alcohol on brain-endocrine-immune interaction in
HIV infection.

For more information on NIAAA's HIV-related
programs contact:
Chief, Epidemiology Branch
Division of Biometry and Epidemiology
NIAAA
Room 14C-26, Parklawn Building
5600 Fishers Ln.
Rockville, MD 20857
301/443-4897
Prevention Research Branch
Division of Clinical and Prevention Research/
AIDS Coordinator
NIAAA
Room 16C-03, Parklawn Building
5600 Fishers Ln.
Rockville, MD 20857
301/443-1677
To obtain an application kit for NIAAA grants
contact:
National Clearinghouse for Alcohol and
Drug Information
Reference Dept.
6000 Executive Blvd., P.O. Box 2345
Rockville, MD 20852
301/468-2600
Office for Substance
Abuse Prevention
The Office for Substance Abuse Prevention
(OSAP) was created by the Anti-Drug Abuse Act of
1986 to lead the Federal Government's effort to
reduce the demand for illicit drugs and prevent
alcohol and other drug problems in the United States.
The Anti-Drug Abuse Act of 1988 expanded OSAP's
functions and mandate.
OSAP programs and activities include: promotion
and distribution of prevention materials such as
posters, brochures, resource lists, and directories;
development of materials and dissemination of information from a database on prevention information
and treatment for a variety of audiences, including
information on AIDS and IV-drug use; continuing
education training for professionals in health and
allied health fields, including multicultural training
workshops for professionals, parents and youth; support of community-based prevention programs; support of the National Clearinghouse for Alcohol and

@1991 ASAP

Reproduction By Permission Only

69

~1991 ASAP Reproduction By Permission Only 69