Jonathan Blake, Jr. (May 29, 1780-April 13, 1864), of Warwick, Massachusetts, and his wife, Patty Conant Blake (d. 1819) married around 1802. Their children included John Pierce (1803-1893), Mary Ann (1805-1807), Jonathan (August 27, 1807-December 30, 1863), Mary Ann (1810-1833), Martha Miriam (1812-1895), and James Edward (1817-1873). Jonathan Blake, Jr., married his second wife, the widow Betsey Howland Ballard, in 1821.
Jonathan Blake (1807-1863), the son of Jonathan Blake, Jr., and Patty Conant Blake, lived in Warwick, Massachusetts; Philadelphia, Pennsylvania; and New York City. He married Mary Jerome (b. May 13, 1804), the daughter of Richard Jerome and Esther Leach of Waterford, Connecticut, on December 20, 1830, and their children were Mary Ann (December 27, 1832-January 5, 1912), Spencer Cone (b. July 17, 1835), and Judson Jerome (b. July 17, 1835).
Mary Ann Blake (1832-1912) married Ephraim Lyon (May 8, 1825-September 1, 1906), the son of Ephraim Lyon (1786-1866) and Margaret Strickland (b. 1787). Their children were Laura, Alice, and Perry.