The Isaiah Williams and Ellen White correspondence is made up of 88 incoming letters to, and letters between, Williams, White, and members of the White family. The letters pertain to the couple's courtship, religion, and social and family news from Massachusetts and Buffalo, New York.
The bulk of the letters are incoming letters to Ellen White from family members, acquaintances, and Isaiah Williams, her future husband. Family and friends often shared social and family news from Boston and Leominster, Massachusetts. One friend mentioned taking dancing lessons and attending a piano concert given by William Mason, a protégé of Franz Liszt (December 6, ). Some of the correspondence pertains to the family's religious beliefs, such as a letter from Ellen's brother Ferdinand to their father about her baptism (October 25, 1845). Isaiah Williams wrote about his life in Buffalo, New York, during the couple's courtship and after their marriage, particularly during Ellen's visits to her family in Boston. On February 14, 1849, an unknown writer mailed a love poem to Ellen. She also received a lengthy letter (undated) from W. G. French, a spiritual advisor who offered religious advice about marriage. Later items include at least 3 letters to Ellen from Elliot Williams, her son. A letter to "Miss Emily J. Mansin" from Sarah L. Poster at the "C.C. Hospital" (possibly the Cliffbourne and Cliffbourne Barracks Hospital) in Washington, D.C., concerns a dead man's belongings (August 12, 1864).