Edmund Quincy was born in Braintree, Massachusetts, on June 13, 1703, the son of Edmund Quincy and Dorothy Flynt. After graduating from Harvard College in 1722, he lived in Boston, where he and his brother Josiah started a merchant firm. When the firm broke up in 1750, Edmund Quincy joined two of his sons in a new merchant partnership, which went bankrupt in 1757. Quincy left Boston for Lancaster in 1775, and he later lived in Medfield and Newton, where he died on July 4, 1788. Edmund Quincy and his first wife, Elizabeth Wendell, married on April 15, 1725. Their children included Henry (d. 1780), Dorothy ("Dolly"), Esther, Elizabeth, Edmund, Abraham, and Jacob. After Wendell's 1769 death, Edmund Quincy married Anna Gerrish (d. 1787) on January 13, 1785. Dorothy Quincy married prominent Massachusetts statesman John Hancock (1737-1793).